Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 9/20 | 0.47 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.44 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 7/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LAP3 | P28838 | 2/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29536183 | 1.00 | CAPN1 (0.47) | CAPN1PSMB1PSMB5PSMB2ALDH1A1 | |
| SCHEMBL25267609 | 0.98 | CAPN1 (0.46) | CAPN1PSMB1PSMB5PSMB2ALDH1A1 | |
| SCHEMBL15957011 | 0.98 | CAPN1 (0.46) | CAPN1PSMB1PSMB5PSMB2ALDH1A1 | |
| SCHEMBL5493312 | 0.86 | ALDH1A1 (0.55) | CAPN1PSMB1PSMB5PSMB2ALDH1A1 | |
| SCHEMBL5493308 | 0.86 | ALDH1A1 (0.55) | CAPN1PSMB1PSMB5PSMB2ALDH1A1 | |
| SCHEMBL3332680 | 0.85 | CAPN1 (0.47) | CAPN1PSMB1PSMB5PSMB2ALDH1A1 | |
| SCHEMBL13077059 | 0.85 | CAPN1 (0.47) | CAPN1PSMB1PSMB5PSMB2ALDH1A1 | |
| SCHEMBL9542347 | 0.85 | ALDH1A1 (0.53) | CAPN1PSMB1PSMB5PSMB2ALDH1A1 | |
| SCHEMBL16024738 | 0.85 | CAPN1 (0.43) | CAPN1PSMB1PSMB5PSMB2ALDH1A1 | |
| SCHEMBL24024845 | 0.85 | CAPN1 (0.43) | CAPN1PSMB1PSMB5PSMB2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070265208-A1 | Association of calpain inhibitors and reactive oxygen species trapping agents | SOCIETE DE CONSEILS DE RECHERCHE ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) | 2007-11-15 | — | — | US | claimed |
| US-7244711-B2 | Association of calpain inhibitors and reactive oxygen species trapping agents | SOCIETE DE CONSEILS DE RECHERCHES ET D' 'APPLICATIONS SCIENTIFIQUES S.C.R.A.S (FR) | 2007-07-17 | — | — | US | claimed |
| EP-1337269-B1 | ASSOCIATION OF CALPAIN INHIBITORS AND REACTIVE OXYGEN SPECIES TRAPPING AGENTS | SOD CONSEILS RECH APPLIC (FR) | 2006-11-08 | — | — | EP | claimed |
| US-20040053851-A1 | Association of calpain inhibitors and reactive oxygen species trapping agents | IPSEN PHARMA S.A.S. (FR) | 2004-03-18 | — | — | US | claimed |
| US-20070265208-A1 | Association of calpain inhibitors and reactive oxygen species trapping agents | SOCIETE DE CONSEILS DE RECHERCHE ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) | 2007-11-15 | — | — | US | disclosed |
| US-7244711-B2 | Association of calpain inhibitors and reactive oxygen species trapping agents | SOCIETE DE CONSEILS DE RECHERCHES ET D' 'APPLICATIONS SCIENTIFIQUES S.C.R.A.S (FR) | 2007-07-17 | — | — | US | disclosed |
| EP-1337269-B1 | ASSOCIATION OF CALPAIN INHIBITORS AND REACTIVE OXYGEN SPECIES TRAPPING AGENTS | SOD CONSEILS RECH APPLIC (FR) | 2006-11-08 | — | — | EP | disclosed |
| US-20040053851-A1 | Association of calpain inhibitors and reactive oxygen species trapping agents | IPSEN PHARMA S.A.S. (FR) | 2004-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265208-A1 | Association of calpain inhibitors and reactive oxygen species trapping agents | CAPNS1, CAPN1, CAPN2 | CAPN1 2/4885PSMB1 116/4885PSMB5 313/4885 |
| US-20040053851-A1 | Association of calpain inhibitors and reactive oxygen species trapping agents | CAPN2, CAPN1, CAPN9 | CAPN1 2/4885PSMB1 219/4885PSMB5 298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.