Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10617975 | 0.84 | TSHR (0.41) | TSHRALDH1A1NPC1CYP3A4KMT2A | |
| SCHEMBL36714 | 0.83 | TSHR (0.45) | TSHRALDH1A1NPC1CYP3A4KMT2A | |
| SCHEMBL2464293 | 0.79 | ALDH1A1 (0.40) | TSHRALDH1A1NPC1CYP3A4HPGD | |
| SCHEMBL11618455 | 0.78 | TSHR (0.42) | TSHRALDH1A1NPC1CYP3A4HPGD | |
| SCHEMBL4975777 | 0.74 | LMNA (0.31) | — | |
| SCHEMBL10731368 | 0.74 | PTPN2 (0.38) | TSHRALDH1A1NPC1HPGDKMT2A | |
| SCHEMBL6900189 | 0.74 | ALDH1A1 (0.45) | TSHRALDH1A1CYP3A4HPGDTDP1 | |
| SCHEMBL10940650 | 0.73 | ALDH1A1 (0.49) | TSHRALDH1A1NPC1CYP3A4KMT2A | |
| SCHEMBL21603039 | 0.73 | TSHR (0.40) | TSHRALDH1A1NPC1CYP3A4KMT2A | |
| SCHEMBL2992727 | 0.72 | TSHR (0.59) | TSHRALDH1A1NPC1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1092421-B1 | Method for preparing ultraviolet radiation absorbing compositions | ROHM & HAAS (US) | 2007-03-21 | — | — | EP | disclosed |