SCHEMBL5570682

SCHEMBL5570682

CNC(=O)c1cn2c(C)c(C)nc2c2c1CC[C@@H](c1ccccc1)O2

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ATP4A P20648 1/20 0.44
ATP4B P51164 1/20 0.44
CYP3A4 P08684 2/20 0.40
CYP2C9 P11712 2/20 0.40
BRD4 O60885 10/20 0.38
RIPK1 Q13546 1/20 0.37
SLC8A1 P32418 4/20 0.34
SCD5 Q86SK9 1/20 0.34
CCNA2 P20248 1/20 0.33
CDK2 P24941 1/20 0.33
CCNA1 P78396 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5566450 1.00 ATP4A (0.44) ATP4AATP4BCYP3A4CYP2C9BRD4
SCHEMBL5567363 1.00 ATP4A (0.44) ATP4AATP4BCYP3A4CYP2C9BRD4
SCHEMBL5415404 0.91 ATP4A (0.42) ATP4AATP4BCYP3A4CYP2C9BRD4
SCHEMBL5411682 0.91 ATP4A (0.44) ATP4AATP4BCYP3A4CYP2C9CCNA2
SCHEMBL5417158 0.91 ATP4A (0.42) ATP4AATP4BCYP3A4CYP2C9BRD4
SCHEMBL5421021 0.91 ATP4A (0.42) ATP4AATP4BCYP3A4CYP2C9BRD4
SCHEMBL5417817 0.91 ATP4A (0.46) ATP4AATP4BCYP3A4CYP2C9RIPK1
SCHEMBL5989112 0.91 ATP4A (0.46) ATP4AATP4BCYP3A4CYP2C9RIPK1
SCHEMBL5414013 0.90 ATP4A (0.41) ATP4AATP4BCYP3A4CYP2C9BRD4
SCHEMBL5422357 0.90 ATP4A (0.41) ATP4AATP4BCYP3A4CYP2C9SLC8A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070066674-A1 Tricyclic imidzopyridines for use as gastric secretion inhibitors ALTANA PHARMA AG (DE) 2007-03-22 US disclosed
EP-1696921-A1 TRICYCLIC IMIDAZOPYRIDINES FOR USE AS GASTRIC SECRETION INHIBITORS Altana Pharma AG (DE) 2006-09-06 EP disclosed
WO-2005058325-A1 TRICYCLIC IMIDAZOPYRIDINES FOR USE AS GASTRIC SECRETION INHIBITORS ALTANA PHARMA AG (DE) 2005-06-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070066674-A1 Tricyclic imidzopyridines for use as gastric secretion inhibitors GIPR, SLC10A2, GRPR ATP4A 96/4885ATP4B 259/4885CYP3A4 72/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.