Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28958265 | 0.85 | CHRM5 (0.32) | CHRM5CHRM3 | |
| SCHEMBL2396109 | 0.84 | KDM4E (0.32) | CHRM5CHRM3 | |
| Hydrochloric Acid SCHEMBL4606199 | 0.84 | CHRM5 (0.31) | CHRM5CHRM3 | |
| SCHEMBL7207583 | 0.78 | SOS1 (0.36) | — | |
| SCHEMBL21813943 | 0.77 | CHRM5 (0.58) | KMT2ACHRM5CHRM3CYP1A2CYP2C19 | |
| SCHEMBL7449892 | 0.75 | SOS1 (0.35) | — | |
| Succinic Acid SCHEMBL14244524 | 0.74 | SOS1 (0.40) | CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9801465 | 0.74 | TSHR (0.36) | — | |
| SCHEMBL9958480 | 0.74 | BIRC2 (0.40) | KMT2A | |
| SCHEMBL1394940 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458689-B1 | ARYLOXYPHENYL AND ARYLSULFANYLPHENYL DERIVATIVES | LUNDBECK & CO AS H (DK) | 2007-04-11 | — | — | EP | disclosed |
| US-7067501-B2 | Aryloxyphenyl and arylsulfanylphenyl derivatives | H. LUNDBECK A/S (DK) | 2006-06-27 | — | — | US | disclosed |
| US-20050171061-A1 | Aryloxyphenyl and arylsulfanylphenyl derivatives | H. LUNDBECK A/S (DK) | 2005-08-04 | — | — | US | disclosed |
| EP-1458689-A1 | ARYLOXYPHENYL AND ARYLSULFANYLPHENYL DERIVATIVES | H. LUNDBECK A/S (DK) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003053942-A1 | ARYLOXYPHENYL AND ARYLSULFANYLPHENYL DERIVATIVES | H. LUNDBECK A/S (DK) | 2003-07-03 | — | — | WO | disclosed |
| EP-0637304-A1 | 1-PIPERAZINEACETIC DERIVATIVES AS FIBRINOGEN RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 1995-02-08 | — | — | EP | disclosed |
| WO-1993022303-A1 | 1-PIPERAZINEACETIC DERIVATIVES AS FIBRINOGEN RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 1993-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171061-A1 | Aryloxyphenyl and arylsulfanylphenyl derivatives | SLC1A5, SLC6A7, SLC6A19 | KMT2A 3754/4885CHRM5 4101/4885CHRM3 3728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.