Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | HBB | P68871 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5573818 | 1.00 | ASIC3 (0.52) | ASIC3CYP1A2CYP1A1CYP1B1ALDH1A1 | |
| SCHEMBL8628482 | 0.93 | ASIC3 (0.61) | ASIC3CYP1A2CYP1A1CYP1B1ALDH1A1 | |
| SCHEMBL430978 | 0.93 | ASIC3 (0.61) | ASIC3CYP1A2CYP1A1CYP1B1ALDH1A1 | |
| SCHEMBL5573799 | 0.92 | ASIC3 (0.53) | ASIC3CYP1A2CYP1A1CYP1B1ALDH1A1 | |
| SCHEMBL1486177 | 0.86 | CYP1A2 (0.44) | ASIC3CYP1A2CYP1A1CYP1B1ALDH1A1 | |
| SCHEMBL30447338 | 0.85 | ASIC3 (0.63) | ASIC3CYP1A2CYP1A1CYP1B1ACACB | |
| SCHEMBL10705668 | 0.85 | ASIC3 (0.63) | ASIC3CYP1A2CYP1A1CYP1B1ACACB | |
| SCHEMBL13156726 | 0.82 | ASIC3 (0.44) | ASIC3CYP1A2CYP1A1CYP1B1ALDH1A1 | |
| SCHEMBL7702432 | 0.82 | CYP1A2 (0.48) | ASIC3CYP1A2CYP1A1CYP1B1ALDH1A1 | |
| SCHEMBL16150863 | 0.81 | CYP1A1 (0.44) | ASIC3CYP1A2CYP1A1CYP1B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654207-B1 | BIS(2-ACENYL)ACETYLENE SEMICONDUCTORS | 3M INNOVATIVE PROPERTIES CO (US) | 2007-08-22 | — | — | EP | disclosed |
| US-7109519-B2 | Bis(2-acenyl)acetylene semiconductors | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-09-19 | — | — | US | disclosed |
| EP-1654207-A1 | BIS(2-ACENYL)ACETYLENE SEMICONDUCTORS | 3M Innovative Properties Company (US) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005014511-A1 | BIS(2-ACENYL)ACETYLENE SEMICONDUCTORS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-02-17 | — | — | WO | disclosed |
| US-20050012090-A1 | Bis(2-acenyl)acetylene semiconductors | 3M INNOVATIVE PROPERTIES COMPANY | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050012090-A1 | Bis(2-acenyl)acetylene semiconductors | LAMP2, ACAT1, SAT1 | ASIC3 1274/4885CYP1A2 2762/4885CYP1A1 2842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.