Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4776622 | 0.91 | GAA (0.44) | GAAEPHX2NR1H4SMN1; SMN2LMNA | |
| SCHEMBL5571908 | 0.90 | GAA (0.43) | GAAEPHX2NR1H4SMN1; SMN2LMNA | |
| SCHEMBL4773019 | 0.89 | GAA (0.46) | GAAEPHX2NR1H4SMN1; SMN2LMNA | |
| SCHEMBL5568007 | 0.89 | GAA (0.46) | GAAEPHX2NR1H4SMN1; SMN2LMNA | |
| SCHEMBL4777546 | 0.84 | GAA (0.45) | GAASMN1; SMN2LMNAMAPTNAMPT | |
| SCHEMBL4773553 | 0.82 | GAA (0.60) | GAASMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL4771090 | 0.79 | GAA (0.46) | GAASMN1; SMN2LMNAMAPTNAMPT | |
| SCHEMBL4767729 | 0.79 | GAA (0.52) | GAASMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL4777522 | 0.79 | GAA (0.52) | GAASMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL4769617 | 0.79 | GAA (0.51) | GAASMN1; SMN2LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070135435-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INCORPORATED | 2007-06-14 | — | — | US | claimed |
| US-20070135435-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INCORPORATED | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135435-A1 | Certain chemical entities, compositions, and methods | KIF5B, KIF2C, PLK1 | GAA 466/4885EPHX2 2831/4885NR1H4 2096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.