SCHEMBL5572088

SCHEMBL5572088

CCCCCCCCCC[SiH](OCCCC)OCCCC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.40
THRB P10828 2/20 0.40
ADRB2 P07550 1/20 0.36
ADRB1 P08588 1/20 0.36
ADRB3 P13945 1/20 0.36
TP53 P04637 1/20 0.33
MEN1 O00255 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
NR5A1 Q13285 1/20 0.33
MAPT P10636 1/20 0.33
PLA2G4B P0C869 1/20 0.32
CES1 P23141 1/20 0.32
LPAR3 Q9UBY5 4/20 0.32
CA1 P00915 4/20 0.32
CA2 P00918 4/20 0.32
CA9 Q16790 4/20 0.32
LPAR2 Q9HBW0 3/20 0.32
LPAR1 Q92633 2/20 0.32
NAAA Q02083 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5575092 1.00 TSHR (0.40) TSHRTHRBADRB2ADRB1ADRB3
SCHEMBL11332079 1.00 TSHR (0.40) TSHRTHRBADRB2ADRB1ADRB3
SCHEMBL704381 0.95 ADRB2 (0.39) TSHRTHRBADRB2ADRB1ADRB3
SCHEMBL708500 0.92 THRB (0.35) TSHRTHRBMEN1HTTKMT2A
SCHEMBL8092136 0.90 THRB (0.40) TSHRTHRBMEN1HTTKMT2A
SCHEMBL3149894 0.90 THRB (0.40) TSHRTHRBMEN1HTTKMT2A
SCHEMBL6298295 0.90 THRB (0.40) TSHRTHRBMEN1HTTKMT2A
SCHEMBL6298936 0.90 THRB (0.40) TSHRTHRBMEN1HTTKMT2A
SCHEMBL4534258 0.90 THRB (0.40) TSHRTHRBMEN1HTTKMT2A
SCHEMBL5574604 0.90 THRB (0.40) TSHRTHRBMEN1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7169327-B2 Composite particle for dielectrics, ultramicroparticulate composite resin particle, composition for forming dielectrics and use thereof JSR CORPORATION (JP) 2007-01-30 US disclosed
EP-1387367-A1 COMPOSITE PARTICLE FOR DIELECTRICS, ULTRAMICROPARTICULATE COMPOSITE RESIN PARTICLE, COMPOSITION FOR FORMING DIELECTRICS AND USE THEREOF JSR Corporation (JP) 2004-02-04 EP disclosed
US-20030151032-A1 Composite particle for dielectrics, ultramicroparticulate composite resin particle, composition for forming dielectrics and use thereof JSR CORPORATION (JP) 2003-08-14 US disclosed