Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 4/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5439819 | 0.73 | HPGD (0.44) | HTTLMNAMAPTALDH1A1MEN1 | |
| SCHEMBL5439813 | 0.73 | HPGD (0.44) | HTTLMNAMAPTALDH1A1MEN1 | |
| SCHEMBL18700298 | 0.73 | PRMT1 (0.47) | HTTLMNAMAPTALDH1A1MEN1 | |
| SCHEMBL5437592 | 0.71 | SMN1; SMN2 (0.39) | NR3C2MMP1KDM5AKDM4CKDM5B | |
| SCHEMBL5437601 | 0.71 | SMN1; SMN2 (0.39) | NR3C2MMP1KDM5AKDM4CKDM5B | |
| SCHEMBL8872290 | 0.69 | MEN1 (0.43) | HTTLMNAMAPTALDH1A1MEN1 | |
| SCHEMBL10485097 | 0.68 | MMP1 (0.48) | NR3C2MMP1KDM5AKDM4CKDM5B | |
| SCHEMBL2473102 | 0.68 | CCNT1 (0.35) | NR3C2MMP1KDM5AKDM4CKDM5B | |
| SCHEMBL8872470 | 0.67 | NAMPT (0.48) | MAPT | |
| SCHEMBL8872542 | 0.67 | LMNA (0.49) | LMNAMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1787991-A1 | PYRROLOÝ2,3-c¨PYRIDINE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE | Takeda Pharmaceutical Company Limited (JP) | 2007-05-23 | — | — | EP | disclosed |