Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5573065 | 1.00 | HSD11B1 (0.39) | HSD11B1HRH3 | |
| SCHEMBL5573022 | 0.88 | HSD11B1 (0.39) | HSD11B1HRH3 | |
| SCHEMBL5573026 | 0.88 | HSD11B1 (0.39) | HSD11B1HRH3 | |
| SCHEMBL17074576 | 0.88 | HSD11B1 (0.39) | HSD11B1HRH3 | |
| SCHEMBL17074575 | 0.88 | HSD11B1 (0.39) | HSD11B1HRH3 | |
| SCHEMBL17074588 | 0.82 | HSD11B1 (0.40) | HSD11B1HRH3 | |
| SCHEMBL17074590 | 0.82 | HSD11B1 (0.40) | HSD11B1HRH3 | |
| SCHEMBL2700964 | 0.81 | HSD11B1 (0.36) | HSD11B1 | |
| SCHEMBL549551 | 0.81 | HSD11B1 (0.45) | HSD11B1HRH3 | |
| SCHEMBL2699389 | 0.81 | HSD11B1 (0.45) | HSD11B1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812005-A2 | LACTAM COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006053024-A2 | LACTAM COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-05-18 | — | — | WO | disclosed |