Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17074576 | 1.00 | HSD11B1 (0.39) | HSD11B1HRH3SCN9A | |
| SCHEMBL17074575 | 1.00 | HSD11B1 (0.39) | HSD11B1HRH3SCN9A | |
| SCHEMBL5573026 | 1.00 | HSD11B1 (0.39) | HSD11B1HRH3SCN9A | |
| SCHEMBL5572384 | 0.89 | HSD11B1 (0.39) | HSD11B1HRH3 | |
| SCHEMBL5573058 | 0.88 | HSD11B1 (0.39) | HSD11B1HRH3 | |
| SCHEMBL5573065 | 0.88 | HSD11B1 (0.39) | HSD11B1HRH3 | |
| SCHEMBL550117 | 0.85 | SCN9A (0.43) | HSD11B1SCN9A | |
| SCHEMBL550118 | 0.85 | SCN9A (0.43) | HSD11B1SCN9A | |
| SCHEMBL549672 | 0.85 | SCN9A (0.43) | HSD11B1SCN9A | |
| SCHEMBL2699529 | 0.85 | SCN9A (0.43) | HSD11B1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812005-A2 | LACTAM COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006053024-A2 | LACTAM COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-05-18 | — | — | WO | disclosed |