Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 6/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17501658 | 0.80 | NR3C1 (0.43) | ALDH1A1KMT2AMEN1RAB9APGR | |
| SCHEMBL10786395 | 0.76 | ALDH1A1 (0.73) | ALDH1A1KMT2AMEN1RAB9APGR | |
| SCHEMBL25168158 | 0.73 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1RAB9APGR | |
| SCHEMBL4260328 | 0.73 | SMARCA2 (0.37) | ALDH1A1KMT2AMEN1HTTMAPT | |
| SCHEMBL86920 | 0.72 | SMARCA2 (0.36) | ALDH1A1KMT2AMEN1HTTMAPT | |
| SCHEMBL8005819 | 0.72 | SMARCA2 (0.36) | ALDH1A1KMT2AMEN1HTTMAPT | |
| SCHEMBL3890561 | 0.72 | SMARCA2 (0.36) | ALDH1A1KMT2AMEN1HTTNPSR1 | |
| SCHEMBL6026250 | 0.67 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1RAB9AHTT | |
| SCHEMBL7567210 | 0.67 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1RAB9AHTT | |
| SCHEMBL7567255 | 0.67 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786773-A1 | ISOINDOLIN-1-ONE DERIVATIVES | Cancer Research Technology Limited (GB) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006024837-A1 | ISOINDOLIN-1-ONE DERIVATIVES | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2006-03-09 | — | — | WO | disclosed |