SCHEMBL5573290

SCHEMBL5573290

O=C1C=c2ccc3c(c2=CC1)Cc1ccccc1O3

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
MAPKAPK2 P49137 1/20 0.34
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ACSL1 P33121 1/20 0.30
GAA P10253 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5111536 0.69 MAOA (0.46) MAOAMAOBGAANPSR1
SCHEMBL3690493 0.69 MAOA (0.59) MAOAMAOBMAPKAPK2NPC1LMNA
SCHEMBL29453995 0.68 MAOA (0.64) MAOAMAOBMAPKAPK2NPC1LMNA
SCHEMBL10462577 0.66 MAOA (0.73) MAOAMAOBMAPKAPK2NPC1LMNA
Xanthene SCHEMBL29378346 0.65 MAOA (1.00) MAOAMAOBMAPKAPK2NPC1LMNA
Xanthene SCHEMBL30586075 0.65 MAOA (1.00) MAOAMAOBMAPKAPK2NPC1LMNA
Xanthene SCHEMBL9339684 0.65 MAOA (1.00) MAOAMAOBMAPKAPK2NPC1LMNA
Xanthene SCHEMBL4267 0.65 MAOA (1.00) MAOAMAOBMAPKAPK2NPC1LMNA
Xanthene SCHEMBL27493963 0.65 MAOA (1.00) MAOAMAOBMAPKAPK2NPC1LMNA
SCHEMBL13777197 0.64 MAOA (0.63) MAOAMAOBMAPKAPK2NPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140120564-A1 NON-INVASIVE MEASUREMENT OF ANALYTES CERCACOR LABORATORIES, INC. (US) 2014-05-01 US disclosed
US-8509867-B2 Non-invasive measurement of analytes CERCACOR LABORATORIES, INC. (US) 2013-08-13 US disclosed
US-20070020181-A1 Non-invasive measurement of analytes CERCACOR LABORATORIES, INC. 2007-01-25 US disclosed
WO-2004044557-A2 NON-INVASIVE MEASUREMENT OF ANALYTES ARGOSE, INC. (US) 2004-05-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070020181-A1 Non-invasive measurement of analytes SLC2A3, SLC2A2, SLC2A4 MAOA 3528/4885MAOB 3740/4885MAPKAPK2 3440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.