Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1392847 | 0.91 | CHRM2 (0.70) | CHRM2KDM4EALOX15CYP1A2CYP2D6 | |
| SCHEMBL6742452 | 0.90 | CYP1A2 (0.60) | CHRM2KDM4EALOX15CYP1A2CYP2D6 | |
| SCHEMBL3314110 | 0.89 | L3MBTL1 (0.62) | CHRM2KDM4EALOX15ALDH1A1L3MBTL1 | |
| SCHEMBL29860055 | 0.89 | L3MBTL1 (0.62) | CHRM2KDM4EALOX15ALDH1A1L3MBTL1 | |
| SCHEMBL30338402 | 0.89 | KDM4E (0.66) | CHRM2KDM4EALOX15CYP1A2CYP2D6 | |
| SCHEMBL5575878 | 0.89 | KDM4E (0.66) | CHRM2KDM4EALOX15CYP1A2CYP2D6 | |
| SCHEMBL3906840 | 0.88 | ALDH1A1 (0.55) | CHRM2KDM4EALOX15CYP1A2CYP2D6 | |
| SCHEMBL6832167 | 0.87 | CYP1A2 (0.55) | CHRM2KDM4EALOX15CYP1A2CYP2D6 | |
| SCHEMBL2854302 | 0.87 | CYP1A2 (0.56) | CHRM2KDM4EALOX15CYP1A2CYP2D6 | |
| SCHEMBL2854495 | 0.87 | KDM4E (0.59) | CHRM2KDM4EALOX15CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183273-B2 | Chemokine receptor binding heterocyclic compounds | ANORMED, INC. (CA) | 2007-02-27 | — | — | US | disclosed |