Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NQO1 | P15559 | 1/20 | 0.31 |
| ▸ | POR | P16435 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1187892 | 0.93 | — | — | |
| SCHEMBL9812791 | 0.91 | KDM4E (0.39) | KDM4EMAPK1LMNAFTOAPP | |
| SCHEMBL10810437 | 0.91 | KDM4E (0.39) | KDM4EMAPK1LMNAFTOAPP | |
| SCHEMBL9812785 | 0.91 | — | — | |
| SCHEMBL7796741 | 0.91 | — | — | |
| SCHEMBL9812784 | 0.87 | KDM4E (0.36) | KDM4EMAPK1LMNAFTOAPP | |
| SCHEMBL10808734 | 0.85 | KDM4E (0.35) | KDM4EMAPK1LMNAFTO | |
| SCHEMBL2405291 | 0.69 | — | — | |
| SCHEMBL13629841 | 0.67 | ALDH1A1 (0.38) | KDM4EMAPK1LMNAALDH1A1MAPT | |
| SCHEMBL546936 | 0.64 | PTPN1 (0.39) | KDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070231407-A1 | Method of treating gallium-nitrate resistant tumors using gallium-containing compounds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-10-04 | — | — | US | disclosed |