Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.36 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8830659 | 0.80 | CES2 (0.37) | PTPN1CES2CES1KMT2ATDP1 | |
| SCHEMBL13629841 | 0.80 | ALDH1A1 (0.38) | PTPN1CES2CES1KMT2ATDP1 | |
| SCHEMBL3661961 | 0.80 | CES2 (0.37) | PTPN1CES2CES1KMT2ATDP1 | |
| SCHEMBL5131964 | 0.77 | PTPN1 (0.44) | PTPN1CES2CES1KMT2ATDP1 | |
| SCHEMBL17160997 | 0.75 | MAPT (0.44) | CES2CES1KMT2AMEN1ALDH1A1 | |
| SCHEMBL7993409 | 0.75 | CES2 (0.44) | CES2CES1KMT2AMEN1ALDH1A1 | |
| SCHEMBL22806903 | 0.71 | AKR1B1 (0.46) | KMT2AMEN1ALDH1A1POLBKDM4E | |
| SCHEMBL70569 | 0.70 | KDM4E (0.52) | KMT2ATDP1ALDH1A1POLBAPEX1 | |
| SCHEMBL1187892 | 0.69 | — | — | |
| SCHEMBL11646687 | 0.69 | KDM4E (0.50) | KMT2ATDP1ALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 229 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1838676-A1 | NEPETALACTAMS AND N-SUBSTITUTED DERIVATIVES THEREOF | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2007-10-03 | — | — | EP | claimed |
| WO-2006072039-A1 | NEPETALACTAMS AND N-SUBSTITUTED DERIVATIVES THEREOF | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-07-06 | — | — | WO | claimed |
| EP-3986551-B1 | TRIAZOLE CARBOXYLIC ACIDS AS LPA ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2025-10-29 | — | — | EP | disclosed |
| US-12435057-B2 | Triazole carboxylic acids as LPA antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-10-07 | — | — | US | disclosed |
| US-12384768-B2 | Isoxazole carboxylic acids as LPA antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-08-12 | — | — | US | disclosed |
| US-20250161269-A1 | COMPOSITIONS AND METHODS FOR PERIPHERAL TARGETING OF MELATONIN RECEPTOR AGONIST | CELMATIX INC. | 2025-05-22 | — | — | US | disclosed |
| US-20240374583-A1 | USE OF MORPHINAN DERIVATIVES FOR TREATMENT OF OPIOID DELTA RECEPTOR AGONIST-RELATED DISEASE | NIPPON CHEMIPHAR CO., LTD (JP) | 2024-11-14 | — | — | US | disclosed |
| US-12109209-B2 | Use of morphinan derivatives for treatment of opioid delta receptor agonist-related disease | NIPPON CHEMIPHAR CO., LTD. (JP) | 2024-10-08 | — | — | US | disclosed |
| US-20240318213-A1 | MODIFIED PROTEIN HAVING ALPHA1,2-FUCOSYLTRANSFERASE ACTIVITY AND METHOD FOR PRODUCING FUCOSE-CONTAINING CARBOHYDRATE | KYOWA HAKKO BIO CO., LTD. (JP) | 2024-09-26 | — | — | US | disclosed |
| EP-3986552-B1 | ISOXAZOLE CARBOXYLIC ACIDS AS LPA ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2024-09-18 | — | — | EP | disclosed |
| EP-4414037-A2 | MORPHINAN DERIVATIVES FOR THE TREATMENT OF OPIOID DELTA RECEPTOR AGONIST-RELATED DISEASES | Nippon Chemiphar Co., Ltd. (JP) | 2024-08-14 | — | — | EP | disclosed |
| EP-0700908-A1 | 1-Arylpyrimidine derivatives and pharmaceutical use thereof | JAPAN ENERGY CORPORATION (JP) | 1996-03-13 | — | — | EP | disclosed |
| US-4198426-A | 2-Substituted-3-methyl-γ-pyrone tricyclic derivatives | AYERST MCKENNA & HARRISON LTD. (CA) | 1980-04-15 | — | — | US | disclosed |
| US-4189490-A | 2-Substituted-3-methyl-γ-pyrone tricyclic derivatives | AYERST MCKENNA & HARRISON LIMITED (CA) | 1980-02-19 | — | — | US | disclosed |
| US-4177284-A | 2-Substituted-3-methyl-γ-pyrone tricvclic derivatives and process therefor | AYERST MCKENNA & HARRISON LTD. (CA) | 1979-12-04 | — | — | US | disclosed |
| US-4105778-A | ANTIALLERGENS, BACTERICIDES, FUNGICIDES | AYERST, MCKENNA & HARRISON, LTD. (CA) | 1978-08-08 | — | — | US | disclosed |
| US-4105778-A | ANTIALLERGENS, BACTERICIDES, FUNGICIDES | AYERST, MCKENNA & HARRISON, LTD. (CA) | 1978-08-08 | — | — | US | disclosed |
| US-4086349-A | Quinolopyran-4-one-2-carboxylic acid derivatives and salts thereof as novel compounds and as medicines for treatment of allergic asthma | MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JA) | 1978-04-25 | — | — | US | disclosed |
| US-4060619-A | ANTIALLERGY, MICROBIOCIDE | AYERST MCKENNA AND HARRISON LTD. (CA) | 1977-11-29 | — | — | US | disclosed |
| US-3953428-A | ANTIBACTERIAL | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) | 1976-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12435057-B2 | Triazole carboxylic acids as LPA antagonists | LPAR3, LPAR1, LPAR5 | PTPN1 1643/4885CES2 1663/4885CES1 179/4885 |
| US-20240374583-A1 | USE OF MORPHINAN DERIVATIVES FOR TREATMENT OF OPIOID DELTA RECEPTOR AGONIST-RELATED DISEASE | OPRD1, OPRM1, OPRK1 | PTPN1 3775/4885CES2 2121/4885CES1 3582/4885 |
| US-12384768-B2 | Isoxazole carboxylic acids as LPA antagonists | LPAR3, LPAR1, LPAR5 | PTPN1 1596/4885CES2 2693/4885CES1 406/4885 |
| US-12109209-B2 | Use of morphinan derivatives for treatment of opioid delta receptor agonist-related disease | OPRD1, OPRM1, OPRK1 | PTPN1 3775/4885CES2 2121/4885CES1 3582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.