Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.32 |
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1890738 | 0.76 | MAPT (0.44) | AURKAAURKBMEN1ALDH1A1MAPT | |
| SCHEMBL9518440 | 0.70 | DDAH1 (0.39) | AURKAAURKBMEN1ALDH1A1MAPT | |
| SCHEMBL13954373 | 0.66 | CES2 (0.53) | MEN1ALDH1A1MAPTHPGDALOX12 | |
| SCHEMBL6618539 | 0.65 | MEN1 (0.38) | MEN1ALDH1A1MAPTHPGDALOX12 | |
| SCHEMBL10946387 | 0.65 | MAPT (0.44) | AURKAAURKBMEN1ALDH1A1MAPT | |
| SCHEMBL9654631 | 0.65 | AURKA (0.34) | AURKAAURKBMEN1ALDH1A1MAPT | |
| SCHEMBL57290 | 0.65 | MEN1 (0.56) | AURKAAURKBMEN1ALDH1A1MAPT | |
| SCHEMBL4911549 | 0.65 | MEN1 (0.47) | AURKAAURKBMEN1ALDH1A1MAPT | |
| SCHEMBL9928465 | 0.63 | MEN1 (0.42) | MEN1ALDH1A1MAPTHPGDALOX12 | |
| SCHEMBL9653460 | 0.63 | CYP2D6 (0.44) | AURKAAURKBMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828759-A1 | BIOSENSORS COMPRISING SEMICONDUCTING ELECTRODES OR RUTHENIUM CONTAINING MEDIATORS AND METHOD OF USING THE SAME | Home Diagnostics, Inc. (US) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006057722-A1 | BIOSENSORS COMPRISING SEMICONDUCTING ELECTRODES OR RUTHENIUM CONTAINING MEDIATORS AND METHOD OF USING THE SAME | HOME DIAGNOSTICS, INC. (US) | 2006-06-01 | — | — | WO | disclosed |