SCHEMBL5574093

SCHEMBL5574093

[C](=C\[C]=C/c1ccccc1)\c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.36
ALDH1A1 P00352 2/20 0.33
TSHR P16473 2/20 0.33
MAOB P27338 2/20 0.33
CYP2A6 P11509 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
LMNA P02545 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CYP19A1 P11511 1/20 0.30
MAOA P21397 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL339509 0.80 APP (0.43) APPALDH1A1TSHRMAOBCYP2A6
SCHEMBL10492226 0.80 APP (0.43) APPALDH1A1TSHRMAOBCYP2A6
SCHEMBL496414 0.80 APP (0.43) APPALDH1A1TSHRMAOBCYP2A6
SCHEMBL397997 0.71 MAOB (0.48) ALDH1A1MAOBMEN1KMT2ALMNA
SCHEMBL5948500 0.70 ALDH1A1 (0.35) ALDH1A1TSHRMAOBCYP2A6MEN1
SCHEMBL8892833 0.69 ALDH1A1 (0.50) ALDH1A1TSHRMAOBCYP2A6MEN1
SCHEMBL8122575 0.69 TSHR (0.50) APPALDH1A1TSHRMAOBMAOA
SCHEMBL6374501 0.69 ALDH1A1 (0.50) ALDH1A1TSHRMAOBCYP2A6MEN1
SCHEMBL8122572 0.69 TSHR (0.50) APPALDH1A1TSHRMAOBMAOA
SCHEMBL3907718 0.69 ALDH1A1 (0.50) ALDH1A1TSHRMAOBCYP2A6MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7169865-B2 Transition metal compounds having a donor-acceptor interaction and a specific substitution pattern BAYER AKTIENGESELLSCHAFT (DE) 2007-01-30 US disclosed
US-7169866-B2 Process for preparing homopolymers, copolymers and/or block copolymers by living polymerization with metallocenes having a donor-acceptor interaction BAYER AKTIENGESELLSCHAFT (DE) 2007-01-30 US disclosed
EP-1549683-A1 METHOD FOR PRODUCING HOMOPOLYMERS, COPOLYMERS AND/OR BLOCK COPOLYMERS COMPRISING METALLOCENES WITH A DONOR-ACCEPTOR INTERACTION, ACCORDING TO A LIVING POLYMERISATION PROCESS Lanxess Deutschland GmbH (DE) 2005-07-06 EP disclosed
EP-1546165-A1 TRANSITION METAL COMPOUNDS WITH DONOR-ACCEPTOR INTERACTION AND A SPECIAL SUBSTITUTION PATTERN Lanxess Deutschland GmbH (DE) 2005-06-29 EP disclosed
WO-2004029100-A1 METHOD FOR PRODUCING HOMOPOLYMERS, COPOLYMERS AND/OR BLOCK COPOLYMERS COMPRISING METALLOCENES WITH A DONOR-ACCEPTOR INTERACTION, ACCORDING TO A LIVING POLYMERISATION PROCESS LANXESS DEUTSCHLAND GMBH (DE) 2004-04-08 WO disclosed
WO-2004029065-A1 TRANSITION METAL COMPOUNDS WITH DONOR-ACCEPTOR INTERACTION AND A SPECIAL SUBSTITUTION PATTERN LANXESS DEUTSCHLAND GMBH (DE) 2004-04-08 WO disclosed
US-20040063877-A1 Process for preparing homopolymers, copolymers and/or block copolymers by living polymerization with metallocenes having a donor-acceptor interaction LANXESS DEUTSCHLAND GMBH (DE) 2004-04-01 US disclosed
US-20040059073-A1 Transition metal compounds having a donor-acceptor interaction and a specific substitution pattern LANXESS DEUTSCHLAND GMBH (DE) 2004-03-25 US disclosed
EP-1041086-B1 Supported catalysts with donor-acceptor interaction BAYER AG (DE) 2004-02-18 EP disclosed
EP-1373284-A1 CATALYSTS CHARACTERIZED BY A DONOR-ACCEPTOR INTERACTION Bayer Aktiengesellschaft (DE) 2004-01-02 EP disclosed
EP-0912585-A1 METALLOCENE COMPOUNDS BAYER AG (DE) 1999-05-06 EP disclosed
EP-0909284-A1 METHOD FOR PRODUCING THERMOPLASTIC ELASTOMERS BAYER AG (DE) 1999-04-21 EP disclosed
EP-0909282-A1 METHOD FOR PRODUCING CYCLOOLEFIN (CO)POLYMERS FOR TECHNICAL APPLICATIONS BAYER AG (DE) 1999-04-21 EP disclosed
EP-0909281-A1 METHOD FOR PRODUCING ELASTOMERS BAYER AG (DE) 1999-04-21 EP disclosed
WO-1998001487-A9 METHOD FOR PRODUCING ELASTOMERS 1998-07-02 WO disclosed
WO-1998001486-A9 METHOD FOR PRODUCING THERMOPLASTIC ELASTOMERS 1998-03-26 WO disclosed
WO-1998001455-A1 METALLOCENE COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1998-01-15 WO disclosed
WO-1998001486-A1 METHOD FOR PRODUCING THERMOPLASTIC ELASTOMERS BAYER AKTIENGESELLSCHAFT (DE) 1998-01-15 WO disclosed
WO-1998001484-A1 METHOD FOR PRODUCING CYCLOOLEFIN (CO)POLYMERS FOR TECHNICAL APPLICATIONS BAYER AKTIENGESELLSCHAFT (DE) 1998-01-15 WO disclosed
WO-1998001487-A1 METHOD FOR PRODUCING ELASTOMERS BAYER AKTIENGESELLSCHAFT (DE) 1998-01-15 WO disclosed