Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL339509 | 1.00 | APP (0.43) | APPALDH1A1TSHRMAOBCYP2A6 | |
| SCHEMBL10492226 | 1.00 | APP (0.43) | APPALDH1A1TSHRMAOBCYP2A6 | |
| SCHEMBL10535666 | 0.84 | NFE2L2 (0.52) | ALDH1A1TSHRL3MBTL1MAPTNFE2L2 | |
| SCHEMBL4482993 | 0.84 | TSHR (0.37) | APPTSHR | |
| SCHEMBL9099736 | 0.84 | ACHE (0.42) | ALDH1A1TSHRCYP2A6LMNAMAPT | |
| SCHEMBL5574093 | 0.80 | APP (0.36) | APPALDH1A1TSHRMAOBCYP2A6 | |
| SCHEMBL16341056 | 0.79 | LCK (0.42) | ALDH1A1TSHRLMNAFFAR1CYP3A4 | |
| SCHEMBL10875666 | 0.79 | CYP11B2 (0.57) | ALDH1A1CYP2A6MAPTCYP19A1MAPK1 | |
| SCHEMBL4660572 | 0.79 | TP53 (0.48) | ALDH1A1TSHRMAOBLMNAMAPT | |
| SCHEMBL18346350 | 0.79 | TRPA1 (0.57) | ALDH1A1TSHRCYP2A6LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200174386-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2020-06-04 | — | — | US | claimed |
| CN-110892335-A | Electrophotographic photoreceptor, process cartridge, and image forming apparatus | 京瓷办公信息系统株式会社 | 2020-03-17 | — | — | CN | claimed |
| CN-110128754-A | A kind of plastic cement race track granular materials and preparation method thereof | 湖南七纬科技有限公司 | 2019-08-16 | — | — | CN | claimed |
| CN-109704806-A | A kind of architectural engineering external-wall heat-insulation material and preparation method thereof | 湖南辰砾新材料有限公司 | 2019-05-03 | — | — | CN | claimed |
| US-9923147-B2 | Organic light emitting device | SAMSUNG DISPLAY CO., LTD. (KR) | 2018-03-20 | — | — | US | claimed |
| US-9660195-B2 | Anthracene derivative having a phenanthryl group | IDEMITSU KOSAN CO., LTD. (JP) | 2017-05-23 | — | — | US | claimed |
| US-20160329501-A1 | ORGANIC LIGHT EMITTING DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2016-11-10 | — | — | US | claimed |
| EP-2438106-B1 | OLIGOMERS WITH DI-PHENYLETHYNYL ENDCAPS | BOEING CO (US) | 2015-03-11 | — | — | EP | claimed |
| US-8822041-B2 | Anthracene derivatives, luminescent materials and organic electroluminescent devices | IDEMITSU KOSAN CO., LTD. (JP) | 2014-09-02 | — | — | US | claimed |
| US-20140128418-A1 | PYRAZOLE DERIVATIVES, PREPARATION METHOD THEREOF, AND COMPOSITION FOR PREVENTING AND TREATING OSTEOPOROSIS CONTAINING SAME | EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION (KR) | 2014-05-08 | — | — | US | claimed |
| WO-1992004325-A1 | NAPHTHALENEPROPIONIC ACID DERIVATIVES AS ANTI-INFLAMMATORY/ANTIALLERGIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-03-19 | — | — | WO | claimed |
| EP-0301813-B1 | NAPHTHALENEPROPIONIC ACID DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-08-08 | — | — | EP | claimed |
| EP-0301813-A1 | Naphthalenepropionic acid derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-02-01 | — | — | EP | claimed |
| EP-0055562-B1 | CEPHALOSPORIN DERIVATIVES | ICI PHARMA (FR) | 1986-02-12 | — | — | EP | claimed |
| EP-0055099-B1 | PENICILLIN DERIVATIVES | ICI PHARMA (FR) | 1984-10-24 | — | — | EP | claimed |
| EP-0075434-A2 | Cephalosporins, their preparation and their pharmaceutical compositions | ICI PHARMA (FR) | 1983-03-30 | — | — | EP | claimed |
| EP-0072608-A2 | Process for the preparation of cephalosporin derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-02-23 | — | — | EP | claimed |
| EP-0071370-A2 | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them | ICI PHARMA (FR) | 1983-02-09 | — | — | EP | claimed |
| EP-0055562-A2 | Cephalosporin derivatives | ICI PHARMA (FR) | 1982-07-07 | — | — | EP | claimed |
| EP-0055099-A1 | Penicillin derivatives | ICI PHARMA (FR) | 1982-06-30 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140128418-A1 | PYRAZOLE DERIVATIVES, PREPARATION METHOD THEREOF, AND COMPOSITION FOR PREVENTING AND TREATING OSTEOPOROSIS CONTAINING SAME | PTH1R, SOST, CYP24A1 | APP 463/4885ALDH1A1 3068/4885TSHR 2456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.