SCHEMBL5574237

SCHEMBL5574237

CCCCCCc1ccc(-c2ccc(-c3ccc4cc5ccccc5cc4c3)s2)s1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RPS6KB2 Q9UBS0 3/20 0.38
MAPT P10636 1/20 0.36
MAOA P21397 2/20 0.35
TRPV1 Q8NER1 2/20 0.33
MAOB P27338 1/20 0.33
KCNH2 Q12809 1/20 0.33
CETP P11597 1/20 0.33
TLR8 Q9NR97 1/20 0.33
CYP2E1 P05181 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2A6 P11509 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2B6 P20813 1/20 0.33
CYP2C19 P33261 1/20 0.33
EPHX1 P07099 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15402480 0.97 RPS6KB2 (0.40) RPS6KB2MAPTMAOATRPV1MAOB
SCHEMBL15581035 0.97 RPS6KB2 (0.40) RPS6KB2MAPTMAOATRPV1MAOB
SCHEMBL5575423 0.96 PGR (0.33) RPS6KB2KCNH2
SCHEMBL887496 0.93 PGR (0.35) RPS6KB2MAPTKCNH2
SCHEMBL11957996 0.93 PGR (0.35) RPS6KB2MAPTKCNH2
SCHEMBL6421773 0.90 PGR (0.36) RPS6KB2KCNH2
SCHEMBL11958248 0.87 KDM4E (0.37) RPS6KB2MAPTTRPV1CYP2E1CYP3A4
SCHEMBL11957366 0.86 PGR (0.40) KCNH2TLR8CYP3A4
SCHEMBL12277763 0.86 ERN1 (0.35) RPS6KB2MAPT
SCHEMBL12405237 0.85 MAPT (0.43) RPS6KB2MAPTTRPV1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1835941-B Acene thiophene semiconductors 3M INNOVATIVE PROPERTIES CO 2012-03-28 CN disclosed
US-7276395-B2 Acene-thiophene semiconductors 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-10-02 US disclosed
US-7276395-B2 Acene-thiophene semiconductors 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-10-02 US disclosed
CN-1835941-A Acene thiophene semiconductors 3M INNOVATIVE PROPERTIES CO (US) 2006-09-20 CN disclosed
EP-1654248-A1 ACENE-THIOPHENE SEMICONDUCTORS 3M Innovative Properties Company (US) 2006-05-10 EP disclosed
US-20060033086-A1 Depositing a gate electrode material on the substrate;depositing a gate dielectric on the gate electrode material;depositing an organic semiconductor layer comprising acene-thiophene compounds, providing a source electrode and a drain electrode contiguous to the organic semiconductor layer GERLACH CHRISTOPHER P 2006-02-16 US disclosed
US-6998068-B2 Acene-thiophene semiconductors 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-02-14 US disclosed
WO-2005019198-A1 ACENE-THIOPHENE SEMICONDUCTORS 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-03-03 WO disclosed
US-20050035333-A1 Acene-thiophene semiconductors 3M INNOVATIVE PROPERTIES COMPANY 2005-02-17 US disclosed