SCHEMBL5574579

SCHEMBL5574579

C/C(=C\CCC(=O)/C=C/c1ccccc1)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.58
HAO1 Q9UJM8 1/20 0.54
GLA P06280 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
HSP90AA1 P07900 2/20 0.48
AKR1C3 P42330 1/20 0.47
MAPT P10636 5/20 0.47
RAB9A P51151 4/20 0.47
KMT2A Q03164 2/20 0.47
KDM4E B2RXH2 1/20 0.47
MEN1 O00255 1/20 0.47
KCNH2 Q12809 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.46
HDAC3 O15379 2/20 0.46
HDAC4 P56524 2/20 0.46
HDAC1 Q13547 2/20 0.46
HDAC2 Q92769 2/20 0.46
HDAC8 Q9BY41 2/20 0.46
HDAC6 Q9UBN7 2/20 0.46
PLIN1 O60240 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2206789 1.00 ALDH1A1 (0.58) ALDH1A1HAO1GLATDP1HSP90AA1
SCHEMBL5574588 1.00 ALDH1A1 (0.58) ALDH1A1HAO1GLATDP1HSP90AA1
Cinnamic Acid SCHEMBL28548074 0.80 HCAR2 (0.58) ALDH1A1HAO1GLATDP1AKR1C3
SCHEMBL480078 0.79 BACE1 (0.41) KDM4EPOLB
SCHEMBL13039630 0.79 ALDH1A1 (0.88) ALDH1A1HAO1GLATDP1HSP90AA1
SCHEMBL3655195 0.79 AKR1C3 (0.52) ALDH1A1HAO1GLATDP1AKR1C3
SCHEMBL11682645 0.78 ALDH1A1 (0.73) ALDH1A1HAO1GLATDP1HSP90AA1
SCHEMBL11682651 0.78 ALDH1A1 (0.73) ALDH1A1HAO1GLATDP1HSP90AA1
SCHEMBL4458908 0.78 ALDH1A1 (0.73) ALDH1A1HAO1GLATDP1HSP90AA1
SCHEMBL9233257 0.78 AKR1B10 (0.58) ALDH1A1GLATDP1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1541118-B1 Hair cosmetic composition containing an elongated NANO-OBJECT from a cross-linked, synthetic polymer, process for applying this composition and uses OREAL (FR) 2007-01-24 EP disclosed
EP-1541118-A1 Hair cosmetic composition containing an elongated NANO-OBJECT from a cross-linked, synthetic polymer, process for applying this composition and uses L'OREAL (FR) 2005-06-15 EP disclosed