SCHEMBL5574869

SCHEMBL5574869

CCCCSC(=S)SC(C)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
NPSR1 Q6W5P4 1/20 0.42
KMT2A Q03164 3/20 0.41
HTT P42858 2/20 0.41
KDM4E B2RXH2 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
MEN1 O00255 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HDAC3 O15379 2/20 0.39
HDAC4 P56524 2/20 0.39
HDAC1 Q13547 2/20 0.39
HDAC7 Q8WUI4 2/20 0.39
HDAC2 Q92769 2/20 0.39
HDAC10 Q969S8 2/20 0.39
HDAC11 Q96DB2 2/20 0.39
HDAC8 Q9BY41 2/20 0.39
HDAC6 Q9UBN7 2/20 0.39
HDAC9 Q9UKV0 2/20 0.39
HDAC5 Q9UQL6 2/20 0.39
POLB P06746 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19810867 0.94 KDM4E (0.39) ALDH1A1NPSR1KMT2AHTTKDM4E
SCHEMBL4172156 0.94 KDM4E (0.39) ALDH1A1NPSR1KMT2AHTTKDM4E
SCHEMBL26373285 0.85 ALDH1A1 (0.40) ALDH1A1NPSR1KMT2AHTTKDM4E
SCHEMBL20799394 0.84 KMT2A (0.33) KMT2AHTTKDM4ETDP1MEN1
SCHEMBL18381177 0.84 HDAC3 (0.32) ALDH1A1NPSR1KMT2AHTTKDM4E
SCHEMBL17681540 0.81 HDAC3 (0.32) KMT2AHTTKDM4ETDP1MEN1
SCHEMBL11443376 0.79 ADRA2C (0.40) ALDH1A1KMT2AKDM4EMEN1LMNA
SCHEMBL18410107 0.78 QPCT (0.31)
SCHEMBL5575429 0.78 CSNK1E (0.38) ALDH1A1KMT2AHTTPOLBGAA
SCHEMBL14254419 0.78 CA12 (0.47) KMT2ATDP1HDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250332319-A1 POLYMER SYSTEM FOR FORMING A HYDROGEL UNIV STELLENBOSCH (ZA) 2025-10-30 US disclosed
EP-4526370-A1 POLYMER SYSTEM FOR FORMING A HYDROGEL Stellenbosch University (ZA) 2025-03-26 EP disclosed
WO-2023225692-A1 POLYMER SYSTEM FOR FORMING A HYDROGEL STELLENBOSCH UNIVERSITY (ZA) 2023-11-23 WO disclosed
WO-2023115076-A1 TERPOLYMERS FOR LIPID NANODISC FORMATION STELLENBOSCH UNIVERSITY (ZA) 2023-06-22 WO disclosed
EP-3118277-B1 METHOD FOR PRODUCING SURFACE-MODIFIED SUBSTRATE, METHOD FOR PRODUCING CONJUGATE, NOVEL HYDROSILANE COMPOUND, SURFACE TREATMENT AGENT, SURFACE TREATMENT AGENT KIT, AND SURFACE-MODIFIED SUBSTRATE UNIV KYOTO (JP) 2019-10-23 EP disclosed
US-20170022223-A1 METHOD FOR PRODUCING SURFACE-MODIFIED BASE MATERIAL, METHOD FOR PRODUCING JOINED BODY, NEW HYDROSILANE COMPOUND, SURFACE TREATMENT AGENT, SURFACE TREATMENT AGENT KIT, AND SURFACE-MODIFIED BASE MATERIAL SIHS REACT CO., LTD. (JP) 2017-01-26 US disclosed
EP-1636310-B1 ACRYLIC DISPERSING AGENTS IN NANOCOMPOSITES COMMW SCIENT IND RES ORG (AU) 2014-11-05 EP disclosed
US-7288585-B2 A polyolefin; natural or synthetic phyllosilicate or a mixture in nanoparticles, polymeric dispersing agent based on a long chain alkyl meth(acrylate), preferably a statistical, block or comb copolymer having hydrophilic and hydrophobic segments CIBA SPECIALTY CHEMICALS CORP. (US) 2007-10-30 US disclosed
US-20060235127-A1 A polyolefin; natural or synthetic phyllosilicate or a mixture in nanoparticles, polymeric dispersing agent based on a long chain alkyl meth(acrylate), preferably a statistical, block or comb copolymer having hydrophilic and hydrophobic segments POLYMERS CRC LTD (AU) 2006-10-19 US disclosed
EP-1636310-A1 ACRYLIC DISPERSING AGENTS IN NANOCOMPOSITES Polymers Australia PTY Limited (AU) 2006-03-22 EP disclosed
WO-2004113436-A1 ACRYLIC DISPERSING AGENTS IN NANOCOMPOSITES POLYMERS AUSTRALIA PTY. LIMITED (AU) 2004-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170022223-A1 METHOD FOR PRODUCING SURFACE-MODIFIED BASE MATERIAL, METHOD FOR PRODUCING JOINED BODY, NEW HYDROSILANE COMPOUND, SURFACE TREATMENT AGENT, SURFACE TREATMENT AGENT KIT, AND SURFACE-MODIFIED BASE MATERIAL BRSK1, SIK2, KIT ALDH1A1 2395/4885NPSR1 1235/4885KMT2A 1442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.