Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.52 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.50 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | LAP3 | P28838 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL8094686 | 0.98 | OPRM1 (0.67) | OPRM1TP53GPR84FFAR1SPHK1 | |
| Tuaminoheptane SCHEMBL5568060 | 0.98 | OPRM1 (0.73) | OPRM1TP53GPR84FFAR1SPHK1 | |
| Bicarbonate SCHEMBL9188645 | 0.93 | OPRM1 (0.73) | OPRM1TP53GPR84FFAR1SPHK1 | |
| Carbamic Acid SCHEMBL28702337 | 0.91 | OPRM1 (0.70) | OPRM1TP53GPR84FFAR1SPHK1 | |
| Tuaminoheptane SCHEMBL25287775 | 0.91 | OPRM1 (0.76) | OPRM1TP53GPR84FFAR1SPHK1 | |
| Tuaminoheptane SCHEMBL8359697 | 0.91 | OPRM1 (0.76) | OPRM1TP53GPR84FFAR1SPHK1 | |
| Acetic Acid SCHEMBL5571311 | 0.91 | OPRM1 (0.61) | OPRM1TP53ACE2GRIK1GRIK2 | |
| Tuaminoheptane SCHEMBL3365884 | 0.91 | OPRM1 (0.76) | OPRM1TP53GPR84FFAR1SPHK1 | |
| SCHEMBL5574135 | 0.89 | OPRM1 (0.67) | OPRM1TP53GPR84FFAR1SPHK1 | |
| Propionic Acid SCHEMBL5571670 | 0.89 | OPRM1 (0.67) | OPRM1TP53GPR84FFAR1SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4294903-A1 | EFFERVESCENT GERMICIDAL COMPOSITIONS | Reckitt & Colman (Overseas) Hygiene Home Limited (GB) | 2023-12-27 | — | — | EP | disclosed |
| WO-2022175695-A1 | EFFERVESCENT GERMICIDAL COMPOSITIONS | Reckitt & Colman (Overseas) Hygiene Home Limited (GB) | 2022-08-25 | — | — | WO | disclosed |
| US-20070135565-A1 | COMPOSITION FOR FORMING POROUS FILM, POROUS FILM AND METHOD FOR FORMING THE SAME, INTERLEVEL INSULATOR FILM, AND SEMICONDUCTOR DEVICE | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2007-06-14 | — | — | US | disclosed |
| US-7132473-B2 | Composition for forming porous film, porous film and method for forming the same, interlevel insulator film, and semiconductor device | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2006-11-07 | — | — | US | disclosed |
| US-7053039-B2 | Effervescent cleaning tablets | RECKITT BENCKISER INC. (US) | 2006-05-30 | — | — | US | disclosed |
| EP-1568744-A1 | COMPOSITION FOR POROUS FILM FORMATION, POROUS FILM, PROCESS FOR PRODUCING THE SAME, INTERLAYER INSULATION FILM AND SEMICONDUCTOR DEVICE | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2005-08-31 | — | — | EP | disclosed |
| US-20040219372-A1 | Composition for forming porous film, porous film and method for forming the same, interlevel insulator film, and semiconductor device | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. | 2004-11-04 | — | — | US | disclosed |
| US-20040116317-A1 | Effervescent cleaning tablets | RECKITT BENCKISER, INC. | 2004-06-17 | — | — | US | disclosed |
| EP-1390464-A1 | EFFERVESCENT CLEANING TABLETS | Reckitt Benckiser Inc. (US) | 2004-02-25 | — | — | EP | disclosed |
| WO-2002086048-A1 | EFFERVESCENT CLEANING TABLETS | RECKITT BENCKISER INC (US) | 2002-10-31 | — | — | WO | disclosed |
| US-6057281-A | A CLEANING TABLET COMPRISING DISODIUM CITRATE, POTASSIUM BICARBONATE, POLYVINYL ALCOHOL AND AKYLBETAINE SURFACTANT; CLEANING TABLETS ARE LIGHTWEIGHT AND HAVE A LOW-BULK CAPACITY; MORE ECONOMICAL SHIPPING AND STORAGE | AMWAY CORPORATION (US) | 2000-05-02 | — | — | US | disclosed |