Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.53 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | CTSE | P14091 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4624953 | 1.00 | GPR119 (0.53) | GPR119USP30EGFRSRCKDM4E | |
| SCHEMBL4596612 | 0.90 | GPR119 (0.58) | GPR119USP30EGFRSRCKDM4E | |
| SCHEMBL5576072 | 0.90 | GPR119 (0.58) | GPR119USP30EGFRSRCKDM4E | |
| SCHEMBL4611146 | 0.87 | USP30 (0.49) | GPR119USP30EGFRSRCKDM4E | |
| SCHEMBL4611139 | 0.87 | USP30 (0.49) | GPR119USP30EGFRSRCKDM4E | |
| SCHEMBL4596495 | 0.83 | GPR119 (0.49) | GPR119USP30KDM4EMAPTTHRB | |
| SCHEMBL4596490 | 0.83 | GPR119 (0.49) | GPR119USP30KDM4EMAPTTHRB | |
| SCHEMBL5575439 | 0.83 | MEN1 (0.49) | GPR119USP30KDM4EMAPTTHRB | |
| SCHEMBL5575428 | 0.83 | MEN1 (0.49) | GPR119USP30KDM4EMAPTTHRB | |
| SCHEMBL4597967 | 0.82 | GPR119 (0.48) | GPR119USP30KDM4EMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | ANORMED, INC. (CA) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | CCR5, CCR4, CCR1 | GPR119 229/4885USP30 4096/4885EGFR 1309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.