Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5575831 | 1.00 | OPRM1 (0.42) | OPRM1SPHK1LMNADNM1TSHR | |
| SCHEMBL5575315 | 1.00 | OPRM1 (0.42) | OPRM1SPHK1LMNADNM1TSHR | |
| SCHEMBL5575843 | 1.00 | OPRM1 (0.42) | OPRM1SPHK1LMNADNM1TSHR | |
| SCHEMBL28402239 | 0.98 | OPRM1 (0.44) | OPRM1SPHK1LMNADNM1TSHR | |
| SCHEMBL5575828 | 0.83 | LMNA (0.41) | OPRM1SPHK1LMNADNM1TSHR | |
| SCHEMBL15380868 | 0.83 | LMNA (0.41) | OPRM1SPHK1LMNADNM1TSHR | |
| SCHEMBL20548699 | 0.83 | LMNA (0.41) | OPRM1SPHK1LMNADNM1TSHR | |
| SCHEMBL5572934 | 0.83 | LMNA (0.41) | OPRM1SPHK1LMNADNM1TSHR | |
| SCHEMBL29002908 | 0.80 | OPRM1 (0.40) | OPRM1LMNADNM1TSHRTHRB | |
| SCHEMBL3420959 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007019478-A2 | DRUG DELIVERY FROM IMPLANTS USING SELF-ASSEMBLED MONOLAYERS - THERAPEUTIC SAMS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2007-02-15 | — | — | WO | disclosed |