Methylpiperazine

Methylpiperazine

SCHEMBL557567

CCO[SiH](OCC)OCC.CN1CCNCC1

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PHGDH O43175 1/20 0.34
SIGMAR1 Q99720 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Piperazine SCHEMBL27891323 0.81 HIF1A (0.35)
N-Methyl Pyrrolidine (Nmp) SCHEMBL25255705 0.79 KDM4E (0.33)
Cyclopropane SCHEMBL4902095 0.79 ALDH1A1 (0.35)
Methylpiperazine SCHEMBL28661865 0.78 PHGDH (0.42) PHGDHSIGMAR1
Methylpiperazine SCHEMBL27965589 0.78 PHGDH (0.42) PHGDHSIGMAR1
Pyrrolidine SCHEMBL2796382 0.77 ALDH1A1 (0.40)
Methylpiperazine SCHEMBL28369856 0.76 PHGDH (0.41) PHGDHSIGMAR1
Azetidine SCHEMBL555258 0.76 CXCR4 (0.30)
Methylpiperazine SCHEMBL12678259 0.75
Methylpiperazine SCHEMBL12678256 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9074032-B2 Membranes based on polyvinyl alcohol WACKER CHEMIE AG (DE) 2015-07-07 US disclosed
US-8137590-B2 Particles comprising zwitterionic structural elements WACKER CHEMIE AG (DE) 2012-03-20 US disclosed
US-20120031843-A1 Membranes based on polyvinyl alcohol WACKER CHEMIE AG (DE) 2012-02-09 US disclosed
US-20080286628-A1 Particles Comprising Zwitterionic Structural Elements WACKER CHEMIE AG (DE) 2008-11-20 US disclosed