Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.41 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | HMGCR | P04035 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | CCKAR | P32238 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31517747 | 0.88 | MAPK14 (0.47) | MAPK14KDM4EGAALMNAALDH1A1 | |
| SCHEMBL9302124 | 0.82 | L3MBTL1 (0.59) | MAPK14LMNAALDH1A1L3MBTL1TDP1 | |
| SCHEMBL31517655 | 0.77 | MAPK14 (0.55) | MAPK14KDM4ELMNAALDH1A1L3MBTL1 | |
| SCHEMBL246148 | 0.76 | CYP2C9 (0.58) | MAPK14KDM4ELMNAALDH1A1L3MBTL1 | |
| SCHEMBL6270540 | 0.74 | HMGCR (0.74) | KDM4ELMNAALDH1A1CYP2C9SIRT6 | |
| SCHEMBL31517659 | 0.74 | CYP2C9 (0.75) | KDM4ELMNAALDH1A1CYP2C9SIRT6 | |
| SCHEMBL1786783 | 0.74 | CYP2C9 (0.75) | KDM4ELMNAALDH1A1CYP2C9SIRT6 | |
| SCHEMBL31517681 | 0.74 | CYP2C9 (0.75) | KDM4ELMNAALDH1A1CYP2C9SIRT6 | |
| SCHEMBL27968969 | 0.70 | MAPK14 (0.42) | MAPK14KDM4ELMNAALDH1A1TDP1 | |
| SCHEMBL13302243 | 0.69 | HMGCR (0.60) | MAPK14KDM4ELMNAALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419407-B1 | IMPROVED PROCESS FOR THE PREPARATION OF FLUVASTATIN AND SALTS THEREOF | PHARMATHEN SA (GR) | 2012-11-14 | — | — | EP | disclosed |
| EP-2419407-A1 | IMPROVED PROCESS FOR THE PREPARATION OF FLUVASTATIN AND SALTS THEREOF | Pharmathen S.A. (GR) | 2012-02-22 | — | — | EP | disclosed |
| US-20120035374-A1 | PROCESS FOR THE PREPARATION OF FLUVASTATIN AND SALTS THEREOF | PHARMATHEN S.A. (GR) | 2012-02-09 | — | — | US | disclosed |
| WO-2010118757-A1 | IMPROVED PROCESS FOR THE PREPARATION OF FLUVASTATIN AND SALTS THEREOF | PHARMATHEN S.A. (GR) | 2010-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035374-A1 | PROCESS FOR THE PREPARATION OF FLUVASTATIN AND SALTS THEREOF | HMGCR, CETP, PCSK9 | MAPK14 1243/4885KDM4E 3685/4885GAA 252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.