Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 6/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29171486 | 0.91 | SIGMAR1 (0.47) | SIGMAR1TSHRCACNA2D1PLA2G1BPLA2G2A | |
| SCHEMBL8518464 | 0.85 | KCNH2 (0.47) | PLA2G1BPLA2G2ACHRM2CHRM3CACNA1F | |
| SCHEMBL1230110 | 0.84 | TSHR (0.40) | SIGMAR1TSHRPLA2G1BPLA2G2AALDH1A1 | |
| SCHEMBL3100521 | 0.83 | CA12 (0.37) | TSHRPLA2G1BPLA2G2ACHRM2CHRM3 | |
| SCHEMBL3112416 | 0.83 | TSHR (0.35) | TSHR | |
| SCHEMBL8398889 | 0.83 | CA12 (0.37) | TSHRPLA2G1BPLA2G2ACHRM2CHRM3 | |
| Hydroxyamine SCHEMBL1454547 | 0.82 | TSHR (0.38) | SIGMAR1TSHRPLA2G1BPLA2G2ANPSR1 | |
| Bromide SCHEMBL28878835 | 0.82 | TSHR (0.38) | SIGMAR1TSHRPLA2G1BPLA2G2AALDH1A1 | |
| SCHEMBL1147030 | 0.82 | SIGMAR1 (0.42) | SIGMAR1LMNACACNA2D1PLA2G1BPLA2G2A | |
| SCHEMBL441038 | 0.79 | SIGMAR1 (0.43) | SIGMAR1LMNACACNA2D1PLA2G1BPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 363 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114933562-B | Efficient preparation method of chloroquine based on (2-hydroxybenzyl) disubstituted phosphine oxide catalysis | 华东理工大学 | 2024-07-23 | — | — | CN | claimed |
| CN-114933562-A | Efficient preparation method of chloroquine based on catalysis of (2-hydroxybenzyl) disubstituted phosphine oxide | 华东理工大学 | 2022-08-23 | — | — | CN | claimed |
| CN-109867790-B | Organic silicon polyether copolymer and preparation method thereof | 南京美思德新材料有限公司 | 2021-07-13 | — | — | CN | claimed |
| EP-1153052-B1 | PROCESS FOR THE PREPARATION OF AN AQUEOUS DISPERSION OF AN ANIONIC POLYURETHANE FREE OF VOLATILE TERTIARY AMINES | STAHL INT BV (NL) | 2004-12-29 | — | — | EP | claimed |
| EP-1006140-B1 | Process for the preparation of siloxane-oxyalkylene copolymers | GEN ELECTRIC (US) | 2004-07-14 | — | — | EP | claimed |
| US-6599977-B1 | Process for the preparation of an aqueous dispersion of an anionic polyurethane. According to the invention, a tertiary amine functional urethane polymer or oligomer acts as acid neutralizing agent. The process with dispersion of anionic | STAHL INTERNATIONAL B.V. (NL) | 2003-07-29 | — | — | US | claimed |
| US-6372874-B1 | SOLVENT-FREE HYDROSILATION OF UNSATURATED POLYETHERS WITH ORGANOHYDROGENSILOXANES IN THE PRESENCE OF HYDROXYL, CARBONYL, OR ETHER-FUNCTIONAL AMINES AS BUFFERS FOR THE METAL HYDROSILATION CATALYSTS; BY-PRODUCT INHIBITION; KINETICS | CROMPTON CORPORATION | 2002-04-16 | — | — | US | claimed |
| EP-1153052-A1 | PROCESS FOR THE PREPARATION OF AN AQUEOUS DISPERSION OF AN ANIONIC POLYURETHANE FREE OF VOLATILE TERTIARY AMINES | STAHL INTERNATIONAL B.V. (NL) | 2001-11-14 | — | — | EP | claimed |
| WO-2001027179-A1 | PROCESS FOR THE PREPARATION OF AN AQUEOUS DISPERSION OF AN ANIONIC POLYURETHANE FREE OF VOLATILE TERTIARY AMINES | STAHL INTERNATIONAL B.V. (NL) | 2001-04-19 | — | — | WO | claimed |
| EP-1006140-A2 | Process for the preparation of siloxane-oxyalkylene copolymers | CK WITCO CORPORATION (US) | 2000-06-07 | — | — | EP | claimed |
| EP-0008411-B1 | PROCESS FOR THE PREPARATION OF 5-DIETHYLAMINO-2-PENTANOL | BASF Aktiengesellschaft (DE) | 1982-01-27 | — | — | EP | claimed |
| US-4224251-A | HYDROGENATION, ANHYDROUS CONDITIONS IN PRESENCE OF ALKALI OR ALKALINE EARTH COMPOUND | BASF AKTIENGESELLSCHAFT (DE) | 1980-09-23 | — | — | US | claimed |
| EP-4691607-A1 | DRAW SOLUTE, DRAW SOLUTION, AND WATER TREATMENT METHOD | Nippon Shokubai Co., Ltd. (JP) | 2026-02-11 | — | — | EP | disclosed |
| US-12331218-B2 | Waterborne light radiation polyurethane mixed polyester polymer coating system | SOLARIS TECHNOLOGY LTD. (GB) | 2025-06-17 | — | — | US | disclosed |
| WO-2024202660-A1 | DRAW SOLUTE, DRAW SOLUTION, AND WATER TREATMENT METHOD | 株式会社日本触媒 | 2024-10-03 | — | — | WO | disclosed |
| CN-114933562-B | Efficient preparation method of chloroquine based on (2-hydroxybenzyl) disubstituted phosphine oxide catalysis | 华东理工大学 | 2024-07-23 | — | — | CN | disclosed |
| US-4224251-A | HYDROGENATION, ANHYDROUS CONDITIONS IN PRESENCE OF ALKALI OR ALKALINE EARTH COMPOUND | BASF AKTIENGESELLSCHAFT (DE) | 1980-09-23 | — | — | US | disclosed |
| EP-0008411-A1 | Process for the preparation of 5-diethylamino-2-pentanol | BASF Aktiengesellschaft (DE) | 1980-03-05 | — | — | EP | disclosed |
| US-4072714-A | NICKEL, COPPER, MANGANESE OXIDES AS CATALYST | BASF AKTIENGESELLSCHAFT (DT) | 1978-02-07 | — | — | US | disclosed |
| US-4048116-A | NICKEL, COPPER, MANGANESE | BASF AKTIENGESELLSCHAFT (DT) | 1977-09-13 | — | — | US | disclosed |