Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.47 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29171486 | 0.85 | SIGMAR1 (0.47) | KCNH2CACNA1FCHRM2ADRA2BADRA2C | |
| SCHEMBL557630 | 0.85 | SIGMAR1 (0.41) | KCNH2CACNA1FCHRM2ADRA2BADRA2C | |
| Bromide SCHEMBL9575763 | 0.84 | KCNH2 (0.47) | KCNH2CACNA1FCHRM2ADRA2BADRA2C | |
| SCHEMBL7759986 | 0.83 | SPHK1 (0.42) | KCNH2CACNA1FCHRM2ADRA2BADRA2C | |
| SCHEMBL28870461 | 0.83 | SPHK1 (0.42) | KCNH2CACNA1FCHRM2ADRA2BADRA2C | |
| SCHEMBL7759653 | 0.83 | SPHK1 (0.42) | KCNH2CACNA1FCHRM2ADRA2BADRA2C | |
| SCHEMBL7754965 | 0.83 | SPHK1 (0.42) | KCNH2CACNA1FCHRM2ADRA2BADRA2C | |
| SCHEMBL7759983 | 0.83 | SPHK1 (0.42) | KCNH2CACNA1FCHRM2ADRA2BADRA2C | |
| SCHEMBL8398889 | 0.83 | CA12 (0.37) | KCNH2CACNA1FCHRM2ADRA2BADRA2C | |
| SCHEMBL3100521 | 0.83 | CA12 (0.37) | KCNH2CACNA1FCHRM2ADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748310-B1 | DIESTERS OF CARBONIC ACID ENDOWED WITH ANTIVIRAL AND ANTI-INFLAMMATORY ACTIVITY | ITALFARMACO SPA (IT) | 1999-06-02 | — | — | EP | disclosed |
| US-5827881-A | ADMINISTERING FOR TREATMENT OF VIRAL DISEASES OR AS ANTIINFLAMMATORY AGENTS | ITALFARMACO S.P.A. (IT) | 1998-10-27 | — | — | US | disclosed |
| EP-0748310-A1 | DIESTERS OF CARBONIC ACID ENDOWED WITH ANTIVIRAL AND ANTI-INFLAMMATORY ACTIVITY | ITALFARMACO S.p.A. (IT) | 1996-12-18 | — | — | EP | disclosed |
| WO-1995023128-A1 | DIESTERS OF CARBONIC ACID ENDOWED WITH ANTIVIRAL AND ANTI-INFLAMMATORY ACTIVITY | ITALFARMACO S.P.A. (IT) | 1995-08-31 | — | — | WO | disclosed |