Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ANPEP | P15144 | 4/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5575374 | 0.76 | KDM4E (0.59) | KDM4EANPEPERAP2LMNACYP1A2 | |
| SCHEMBL9350980 | 0.76 | KDM4E (0.59) | KDM4EANPEPERAP2LMNACYP1A2 | |
| SCHEMBL28298132 | 0.73 | SLC6A2 (0.46) | KDM4ECYP2D6ALDH1A1 | |
| SCHEMBL14873238 | 0.73 | IDO1 (0.36) | PDE4A | |
| SCHEMBL14862307 | 0.73 | IDO1 (0.36) | PDE4A | |
| Hydrochloric Acid SCHEMBL15400532 | 0.71 | IDO1 (0.39) | KDM4ELMNAPDE4A | |
| SCHEMBL6783132 | 0.70 | GRIA4 (0.56) | KDM4ELMNACYP1A2CYP2D6SCN1A | |
| SCHEMBL5575277 | 0.70 | GLA (0.43) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL18034384 | 0.69 | IDO1 (0.42) | HRH3 | |
| SCHEMBL2555848 | 0.69 | IDO1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | ANORMED, INC. (CA) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | CCR5, CCR4, CCR1 | KDM4E 3689/4885ANPEP 1479/4885ERAP2 2051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.