Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5573889 | 0.99 | KDM4E (0.45) | GLAHTTNPSR1KDM4EADRB3 | |
| SCHEMBL5575368 | 0.87 | OPRM1 (0.39) | ADRB3OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL9350980 | 0.80 | KDM4E (0.59) | KDM4EL3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL5575374 | 0.80 | KDM4E (0.59) | KDM4EL3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL21539590 | 0.77 | POLB (0.45) | OPRM1OPRD1OPRK1OPRL1EPHX2 | |
| SCHEMBL18298572 | 0.77 | POLB (0.45) | OPRM1OPRD1OPRK1OPRL1EPHX2 | |
| SCHEMBL30747365 | 0.76 | OPRL1 (0.56) | OPRM1OPRD1OPRK1OPRL1SLC6A2 | |
| SCHEMBL26648907 | 0.76 | OPRL1 (0.56) | OPRM1OPRD1OPRK1OPRL1SLC6A2 | |
| SCHEMBL26649365 | 0.76 | OPRL1 (0.56) | OPRM1OPRD1OPRK1OPRL1SLC6A2 | |
| SCHEMBL5848565 | 0.76 | ADRB2 (0.57) | KDM4EADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | ANORMED, INC. (CA) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | CCR5, CCR4, CCR1 | GLA 4694/4885HTT 4524/4885NPSR1 299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.