SCHEMBL5576606

SCHEMBL5576606

NCCCCCCOC=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 5/20 0.42
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA3 P07451 2/20 0.42
CA4 P22748 2/20 0.42
CA6 P23280 2/20 0.42
CA5A P35218 2/20 0.42
CA7 P43166 2/20 0.42
CA9 Q16790 2/20 0.42
CA14 Q9ULX7 2/20 0.42
CA5B Q9Y2D0 2/20 0.42
LMNA P02545 2/20 0.42
TSHR P16473 2/20 0.42
BLM P54132 1/20 0.42
NFKB1 P19838 1/20 0.37
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
ALDH1A1 P00352 2/20 0.33
PLG P00747 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6008541 1.00
SCHEMBL2697173 1.00 DNM1 (0.42) DNM1CA12CA1CA2CA3
SCHEMBL2893721 1.00 DNM1 (0.42) DNM1CA12CA1CA2CA3
SCHEMBL2700797 1.00 DNM1 (0.42) DNM1CA12CA1CA2CA3
SCHEMBL16282044 1.00 DNM1 (0.42) DNM1CA12CA1CA2CA3
SCHEMBL6006472 0.97
SCHEMBL1983084 0.89
SCHEMBL27606588 0.86
SCHEMBL2285548 0.86 ALDH1A1 (0.32) CA12CA1CA2CA3CA4
SCHEMBL2283394 0.86 ALDH1A1 (0.32) CA12CA1CA2CA3CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014074421-A1 PRODRUG BIPYRIDYLAMINOPYRIDINES AS SYK INHIBITORS MERCK SHARP & DOHME CORP. (US) 2014-05-15 WO claimed
CN-101910351-A Dispersion comprising cerium oxide and sheet silicate EVONIK DEGUSSA GMBH 2010-12-08 CN claimed
CN-101910352-A Dispersion comprising cerium oxide and colloidal silicon dioxide EVONIK DEGUSSA GMBH 2010-12-08 CN claimed
CN-101679809-A Dispersion comprising cerium oxide, silicon dioxide and amino acid EVONIK DEGUSSA GMBH 2010-03-24 CN claimed
CN-101679808-A Dispersion comprising cerium oxide, sheet silicate and amino acid EVONIK DEGUSSA GMBH 2010-03-24 CN claimed
CN-102510882-B Migration-free colored copolycondensates for coloring polymers BASF SE 2015-04-15 CN disclosed
WO-2014074421-A1 PRODRUG BIPYRIDYLAMINOPYRIDINES AS SYK INHIBITORS MERCK SHARP & DOHME CORP. (US) 2014-05-15 WO disclosed
US-8420040-B2 Organic-inorganic composite and polymeric composite material, and method producing them NATIONAL INSTITUTE FOR MATERIALS SCIENCE (JP) 2013-04-16 US disclosed
CN-102802875-A Dispersion comprising cerium oxide and silicon dioxide EVONIK DEGUSSA GMBH 2012-11-28 CN disclosed
CN-102510882-A Migration-free colored copolycondensates for coloring polymers BASF SE 2012-06-20 CN disclosed
CN-101910351-A Dispersion comprising cerium oxide and sheet silicate EVONIK DEGUSSA GMBH 2010-12-08 CN disclosed
CN-101910352-A Dispersion comprising cerium oxide and colloidal silicon dioxide EVONIK DEGUSSA GMBH 2010-12-08 CN disclosed
US-5677319-A THIAZOLE DERIVATIVE OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-10-14 US disclosed
US-5643932-A PREVENTS CELL DAMAGE AFTER ISCHEMIA AND RE-PERFUSION, SUBSTITUTED THIAZOLES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-07-01 US disclosed
US-5639770-A SUPEROXIDE INHIBITOR OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-06-17 US disclosed
US-5491201-A HEAT/CHEMICAL RESISTANCE; HIGH MECHANICAL STRENGTH THE DOW CHEMICAL COMPANY (US) 1996-02-13 US disclosed
US-5338828-A Mesogenic cyclic imino ether-containing compositions and polymerization products thereof THE DOW CHEMICAL COMPANY (US) 1994-08-16 US disclosed
EP-0600092-A1 THIAZOLE DERIVATIVE OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-06-08 EP disclosed
US-5281675-A Liquid crystal polymers THE DOW CHEMICAL COMPANY (US) 1994-01-25 US disclosed
EP-0513387-A1 ACTIVE OXYGEN INHIBITOR OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1992-11-19 EP disclosed