Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KDM1A | O60341 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663048 | 0.89 | RAB9A (0.59) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL22441291 | 0.87 | NPC1 (0.60) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL23651430 | 0.84 | NPC1 (0.66) | RAB9ANPC1SMN1; SMN2KMT2ACYP1A2 | |
| SCHEMBL7450964 | 0.84 | NPC1 (0.66) | RAB9ANPC1SMN1; SMN2KMT2ACYP1A2 | |
| SCHEMBL15088518 | 0.82 | NAMPT (0.54) | NAMPTHDAC4HDAC6KDM4ERAB9A | |
| SCHEMBL5497348 | 0.82 | RAB9A (0.56) | NAMPTHDAC4HDAC6KDM4ERAB9A | |
| SCHEMBL30914509 | 0.81 | NPC1 (0.71) | NAMPTHDAC4HDAC6KDM4ERAB9A | |
| SCHEMBL1560664 | 0.81 | KDM1A (0.53) | NAMPTHDAC4HDAC6KDM4ERAB9A | |
| SCHEMBL12124399 | 0.81 | HPGD (0.71) | NAMPTHDAC4HDAC6KDM4ERAB9A | |
| SCHEMBL4514709 | 0.81 | CYP1A2 (0.53) | NAMPTHDAC4HDAC6KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | ANORMED, INC. (CA) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | CCR5, CCR4, CCR1 | NAMPT 2025/4885HDAC4 624/4885HDAC6 768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.