Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.32 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | PEPD | P12955 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10205021 | 0.82 | HSD17B10 (0.37) | DPP4HSD17B10LMNACYP2C19PIK3CA | |
| SCHEMBL8235608 | 0.82 | HSD17B10 (0.37) | DPP4HSD17B10LMNACYP2C19PIK3CA | |
| SCHEMBL4898829 | 0.82 | HSD17B10 (0.37) | DPP4HSD17B10LMNACYP2C19PIK3CA | |
| Hydrochloric Acid SCHEMBL7302950 | 0.80 | HSD17B10 (0.36) | DPP4HSD17B10LMNACYP2C19PIK3CA | |
| SCHEMBL1074624 | 0.80 | DPP4 (0.38) | DPP4HSD17B10LMNACYP2C19PIK3CA | |
| SCHEMBL4901400 | 0.77 | EPHX1 (0.35) | HSD17B10LMNACYP2C19FKBP1ASMN1; SMN2 | |
| SCHEMBL22245620 | 0.74 | DPP4 (0.36) | DPP4HSD17B10LMNACYP2C19PEPD | |
| SCHEMBL18630239 | 0.73 | BCHE (0.36) | HSD17B10LMNACYP2C19FKBP1ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL25394450 | 0.73 | DPP4 (0.35) | DPP4PEPDGAAAR | |
| SCHEMBL18630157 | 0.71 | BCHE (0.40) | LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070021398-A1 | Substituted Pyrazoline Compounds, their Preparation and Use as Medicaments | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021398-A1 | Substituted Pyrazoline Compounds, their Preparation and Use as Medicaments | PIR, SYMPK, P2RX5 | DPP4 38/4885HSD17B10 4786/4885LMNA 1928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.