SCHEMBL5576829

SCHEMBL5576829

Cc1ccccc1S(=O)(=O)N(C)N=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.47
HTR2C P28335 1/20 0.47
PIK3CD O00329 1/20 0.41
PIK3CA P42336 1/20 0.41
MAPT P10636 1/20 0.41
KMT2A Q03164 1/20 0.40
HSD11B1 P28845 1/20 0.39
HCRTR2 O43614 1/20 0.39
ALDH1A1 P00352 4/20 0.39
POLB P06746 1/20 0.39
HTT P42858 1/20 0.38
KEAP1 Q14145 1/20 0.37
NFE2L2 Q16236 1/20 0.37
RAPGEF4 Q8WZA2 1/20 0.37
PTPN1 P18031 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TP53 P04637 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
KDM4E B2RXH2 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16289972 0.82 ALDH1A1 (0.43) HTR2AHTR2CMAPTKMT2AALDH1A1
SCHEMBL701463 0.81 ALDH1A1 (0.55) HTR2AHTR2CMAPTHSD11B1HCRTR2
SCHEMBL7972381 0.78 HTR2A (0.49) HTR2AHTR2CMAPTKMT2AHSD11B1
SCHEMBL28264877 0.76 HTR2A (0.44) HTR2AHTR2CMAPTKMT2AHSD11B1
SCHEMBL2722524 0.76 KMT2A (0.47) HTR2AHTR2CMAPTKMT2AHSD11B1
SCHEMBL6503915 0.75 HTR2A (0.46) HTR2AHTR2CMAPTKMT2AHSD11B1
SCHEMBL31362102 0.75 HTR2A (0.46) HTR2AHTR2CMAPTKMT2AHSD11B1
SCHEMBL5798578 0.75 HTR2A (0.46) HTR2AHTR2CMAPTKMT2AHSD11B1
SCHEMBL4566032 0.74 HCRTR2 (0.48) HTR2AHTR2CMAPTKMT2AHSD11B1
SCHEMBL27932193 0.74 HTR2A (0.46) HTR2AHTR2CPIK3CDPIK3CAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107643356-A The analysis method of chlorine isotope in a kind of chloro phenol organic matter 东华理工大学 2018-01-30 CN claimed
US-9249088-B2 Continuous production and reaction of a diazo compound DPX HOLDINGS B.V. (NL) 2016-02-02 US claimed
EP-2635548-B1 CONTINUOUS PRODUCTION AND REACTION OF A DIAZO COMPOUND DPX HOLDINGS BV (NL) 2014-12-17 EP claimed
US-20140100360-A1 CONTINUOUS PRODUCTION AND REACTION OF A DIAZO COMPOUND DSM FINE CHEMICALS AUSTRIA NFG. GMBH & CO KG (AT) 2014-04-10 US claimed
US-7902342-B2 Method for producing gaseous diazoalkanes DYNAMIT NOBEL GMBH EXPLOSIVSTOFF-UND SYSTEMTECHNIK (DE) 2011-03-08 US claimed
US-20070249817-A1 Method for Producing Gaseous Diazoalkanes DYNAMIT NOBEL GMBH EXPLOSIVSTOFF- UND SYSTEMTECHNIK (DE) 2007-10-25 US claimed
CN-1980885-A Method for producing gaseous diazoalkanes DYNAMIT NOBEL AG (DE) 2007-06-13 CN claimed
US-6962983-B2 Process for the preparation of diazomethane PHOENIX CHEMICALS LIMITED (GB) 2005-11-08 US claimed
WO-2024083012-A1 LITHIUM ION ELECTROLYTIC SOLUTION, GEL POLYMER ELECTROLYTE, AND LITHIUM ION BATTERY 张家港市国泰华荣化工新材料有限公司 2024-04-25 WO disclosed
CN-104254537-B Phragmalin limonoids for the treatment of sexual dysfunction 戴考缇立登公司 2017-06-30 CN disclosed
US-9249088-B2 Continuous production and reaction of a diazo compound DPX HOLDINGS B.V. (NL) 2016-02-02 US disclosed
EP-2635548-B1 CONTINUOUS PRODUCTION AND REACTION OF A DIAZO COMPOUND DPX HOLDINGS BV (NL) 2014-12-17 EP disclosed
US-20140100360-A1 CONTINUOUS PRODUCTION AND REACTION OF A DIAZO COMPOUND DSM FINE CHEMICALS AUSTRIA NFG. GMBH & CO KG (AT) 2014-04-10 US disclosed
US-7902342-B2 Method for producing gaseous diazoalkanes DYNAMIT NOBEL GMBH EXPLOSIVSTOFF-UND SYSTEMTECHNIK (DE) 2011-03-08 US disclosed
US-20070249817-A1 Method for Producing Gaseous Diazoalkanes DYNAMIT NOBEL GMBH EXPLOSIVSTOFF- UND SYSTEMTECHNIK (DE) 2007-10-25 US disclosed
CN-1980885-A Method for producing gaseous diazoalkanes DYNAMIT NOBEL AG (DE) 2007-06-13 CN disclosed
US-20060046209-A1 Image forming method KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2006-03-02 US disclosed
WO-1998017662-A1 PHENYL-SUBSTITUTED BICYCLIC HETEROCYCLYL DERIVATIVES AND THEIR USE NOVARTIS AG (CH) 1998-04-30 WO disclosed
US-5354727-A Herbicides AMERICAN CYANAMID COMPANY (US) 1994-10-11 US disclosed