SCHEMBL701463

SCHEMBL701463

Cc1ccccc1S(=O)(=O)N(C)C

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.55
HTT P42858 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.52
HTR2A P28223 1/20 0.51
HTR2C P28335 1/20 0.51
POLB P06746 2/20 0.50
KCNJ6 P48051 4/20 0.49
KCNJ5 P48544 4/20 0.49
KCNJ3 P48549 4/20 0.49
PDE2A O00408 1/20 0.49
PDE5A O76074 1/20 0.49
CYP3A4 P08684 1/20 0.49
ALOX15 P16050 1/20 0.49
NFKB1 P19838 1/20 0.49
APEX1 P27695 1/20 0.49
PDE4A P27815 1/20 0.49
BLM P54132 1/20 0.49
PDE1B Q01064 1/20 0.49
PMP22 Q01453 1/20 0.49
PDE4B Q07343 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2931331 0.83 ALDH1A1 (0.49) ALDH1A1HTTSMN1; SMN2HTR2AHTR2C
SCHEMBL7972381 0.83 HTR2A (0.49) ALDH1A1HTTSMN1; SMN2HTR2AHTR2C
SCHEMBL5576829 0.81 HTR2A (0.47) ALDH1A1HTTSMN1; SMN2HTR2AHTR2C
SCHEMBL31362102 0.80 HTR2A (0.46) ALDH1A1HTTHTR2AHTR2CPOLB
SCHEMBL5798578 0.80 HTR2A (0.46) ALDH1A1HTTHTR2AHTR2CPOLB
SCHEMBL6503915 0.80 HTR2A (0.46) ALDH1A1HTTHTR2AHTR2CMAPT
SCHEMBL4566032 0.79 HCRTR2 (0.48) ALDH1A1HTTHTR2AHTR2CPOLB
SCHEMBL3822613 0.79 MCOLN3 (0.60) ALDH1A1HTTHTR2AHTR2CMAPT
SCHEMBL28497931 0.79 HTR2A (0.46) ALDH1A1HTTSMN1; SMN2HTR2AHTR2C
SCHEMBL27932193 0.79 HTR2A (0.46) ALDH1A1HTTSMN1; SMN2HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3389787-A1 ANTIVIRAL AGENTS FOR DRUG-RESISTANT INFLUENZA A Thomas Jefferson University (US) 2018-10-24 EP claimed
WO-2017106820-A1 ANTIVIRAL AGENTS FOR DRUG-RESISTANT INFLUENZA A THOMAS JEFFERSON UNIVERSITY (US) 2017-06-22 WO claimed
EP-2976341-A1 ACYCLIC CYANOETHYLPYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS Merck Sharp & Dohme Corp. (US) 2016-01-27 EP claimed
WO-2014146493-A1 ACYCLIC CYANOETHYLPYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS MERCK SHARP & DOHME CORP. (US) 2014-09-25 WO claimed
EP-2086935-A1 SUBSTITUTED SULFONAMIDE DERIVATIVES FOR USE AS BRADYKININ 1 RECEPTOR MODULATORS Grünenthal GmbH (DE) 2009-08-12 EP claimed
WO-2008046573-A1 SUBSTITUTED SULFONAMIDE DERIVATIVES FOR USE AS BRADYKININ 1 RECEPTOR MODULATORS Grünenthal GmbH (DE) 2008-04-24 WO claimed
EP-0694041-A1 A PROCESS AND INTERMEDIATE COMPOUNDS USEFUL FOR THE PREPARATION OF PLATELET GLYCOPROTEIN IIb/IIIa INHIBITORS CONTAINING N-ALPHA-METHYLARGININE THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-01-31 EP claimed
WO-1994022911-A2 A PROCESS AND INTERMEDIATE COMPOUNDS USEFUL FOR THE PREPARATION OF PLATELET GLYCOPROTEIN IIb/IIIa INHIBITORS CONTAINING Nα-METHYLARGININE THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1994-10-13 WO claimed
WO-2026090589-A1 HETEROCYCLIC HBS1L DEGRADERS TANGO THERAPEUTICS, INC. (US) 2026-04-30 WO disclosed
EP-4396354-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF Wave Life Sciences Ltd. (SG) 2024-07-10 EP disclosed
WO-2024130218-A1 STAPLED PEPTIDES AND METHODS THEREOF FOG PHARMACEUTICALS, INC. (US) 2024-06-20 WO disclosed
EP-4340859-A1 ANTIBODY DRUG CONJUGATES USING MATES TECHNOLOGY FOR DELIVERING CYTOTOXIC AGENTS Biohaven Therapeutics Ltd. (US) 2024-03-27 EP disclosed
EP-4337639-A1 NAMPT INHIBITORS AND USES THEREOF Remedy Plan, Inc. (US) 2024-03-20 EP disclosed
WO-2024020188-A2 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF AMYLYX PHARMACEUTICALS, INC. (US) 2024-01-25 WO disclosed
EP-0299533-B1 HIGH POTENCY SWEETENING AGENTS THE NUTRASWEET COMPANY (a Delaware corporation) (US) 1993-04-07 EP disclosed
EP-0316649-A2 Water insoluble azo colouring agents, their preparation and use HOECHST AKTIENGESELLSCHAFT (DE) 1989-05-24 EP disclosed
WO-1989000563-A1 HIGH POTENCY SWEETENING AGENTS THE NUTRASWEET COMPANY (US) 1989-01-26 WO disclosed
EP-0299533-A2 High potency sweetening agents THE NUTRASWEET COMPANY (a Delaware corporation) (US) 1989-01-18 EP disclosed
US-4059610-A Process for preparing isocyanic acid derivatives KAO SOAP CO., LTD. (JA) 1977-11-22 US disclosed
US-3933869-A Preparation of organic radiohalogen compounds SCHERING AKTIENGESELLSCHAFT (DT) 1976-01-20 US disclosed