Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 4/20 | 0.63 |
| ▸ | BACE1 | P56817 | 12/20 | 0.56 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.56 |
| ▸ | CTSD | P07339 | 1/20 | 0.56 |
| ▸ | GNPAT | O15228 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5576870 | 1.00 | OPRK1 (0.63) | OPRK1BACE1BACE2CTSDGNPAT | |
| SCHEMBL30616045 | 0.98 | OPRK1 (0.60) | OPRK1BACE1BACE2CTSD | |
| SCHEMBL30570972 | 0.98 | OPRK1 (0.60) | OPRK1BACE1BACE2CTSD | |
| SCHEMBL29659768 | 0.96 | OPRK1 (0.58) | OPRK1BACE1BACE2CTSD | |
| SCHEMBL30616041 | 0.96 | OPRK1 (0.58) | OPRK1BACE1BACE2CTSD | |
| SCHEMBL30957134 | 0.94 | OPRK1 (0.69) | OPRK1GNPAT | |
| SCHEMBL30957135 | 0.94 | OPRK1 (0.69) | OPRK1GNPAT | |
| SCHEMBL30957126 | 0.94 | OPRK1 (0.69) | OPRK1GNPAT | |
| SCHEMBL30957133 | 0.94 | OPRK1 (0.69) | OPRK1GNPAT | |
| SCHEMBL30957125 | 0.94 | OPRK1 (0.69) | OPRK1GNPAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070092508-A1 | Detoxification depot for Alzheimer's disease | RECOMBIANT TECHNOLOGIES, LLC (US) | 2007-04-26 | — | — | US | disclosed |
| WO-2007047967-A2 | DETOXIFICATION DEPOT FOR ALZHEIMER'S DISEASE | SENICURE, LLC (US) | 2007-04-26 | — | — | WO | disclosed |
| US-20060069010-A1 | Detoxification depot for Alzheimer's disease | SENICURE LLC (US) | 2006-03-30 | — | — | US | disclosed |