SCHEMBL5577164

SCHEMBL5577164

CC(C)N(CC(=O)OC(C)(C)C)C(C)C

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.39
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA7 P43166 2/20 0.35
HDAC6 Q9UBN7 2/20 0.34
HDAC3 O15379 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC2 Q92769 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
CA12 O43570 3/20 0.33
CA14 Q9ULX7 3/20 0.33
PTPRC P08575 2/20 0.32
CTSK P43235 1/20 0.32
DGAT1 O75907 1/20 0.31
PLA2G10 O15496 1/20 0.31
PLA2G5 P39877 1/20 0.31
NR1D1 P20393 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13981283 0.81 CYP2D6 (0.38) CYP2D6CA1CA2CA7HDAC6
SCHEMBL27876066 0.79 CYP2D6 (0.37) CYP2D6CA1CA2CA7HDAC6
SCHEMBL7562972 0.77 CYP2D6 (0.41) CYP2D6CA1CA2CA7HDAC6
SCHEMBL27420033 0.77 NR1D1 (0.38) CYP2D6CA1CA2CA7HDAC6
SCHEMBL20674791 0.76 CA1 (0.35) CYP2D6CA1CA2CA7HDAC6
SCHEMBL19563379 0.76 CYP2D6 (0.35) CYP2D6CA1CA2CA7HDAC6
SCHEMBL9338982 0.75 CYP2D6 (0.37) CYP2D6CA1CA2CA7HDAC6
SCHEMBL13981334 0.75 CYP2D6 (0.37) CYP2D6CA1CA2CA7HDAC6
SCHEMBL4338603 0.75 CYP2D6 (0.34) CYP2D6CA1CA2CA7HDAC6
SCHEMBL7563852 0.75 CYP2D6 (0.34) CYP2D6CA1CA2CA7HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8697604-B2 Labeling agents for mass spectrometry comprising tertiary amines ELECTROPHORETICS LIMITED (GB) 2014-04-15 US disclosed
EP-1606623-B1 LABELLING AGENTS FOR MASS SPECTROMETRY COMPRISING TERTIARY AMINES ELECTROPHORETICS LTD (GB) 2013-05-22 EP disclosed
EP-1606623-B1 LABELLING AGENTS FOR MASS SPECTROMETRY COMPRISING TERTIARY AMINES ELECTROPHORETICS LTD (GB) 2013-05-22 EP disclosed
US-20070023628-A1 Labeling agents for mass spectrometry comprising tertiary amines ELECTROPHORETICS LIMITED (GB) 2007-02-01 US disclosed
US-20070023628-A1 Labeling agents for mass spectrometry comprising tertiary amines ELECTROPHORETICS LIMITED (GB) 2007-02-01 US disclosed
US-20070023628-A1 Labeling agents for mass spectrometry comprising tertiary amines ELECTROPHORETICS LIMITED (GB) 2007-02-01 US disclosed
EP-1606623-A2 LABELLING AGENTS FOR MASS SPECTROMETRY COMPRISING TERTIARY AMINES Xzillion GmbH & CO.KG (DE) 2005-12-21 EP disclosed
WO-2004086050-A2 LABELLING AGENTS FOR MASS SPECTROMETRY COMPRISING TERTIARY AMINES XZILLION GMBH & CO. KG (DE) 2004-10-07 WO disclosed