Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | NR1D1 | P20393 | 5/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.30 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3780438 | 0.85 | CYP2D6 (0.35) | CYP2D6NR1D1CA1CA2CA7 | |
| SCHEMBL5957310 | 0.84 | CYP2D6 (0.33) | CYP2D6NR1D1NR1H3 | |
| SCHEMBL27420033 | 0.83 | NR1D1 (0.38) | CYP2D6NR1D1CA1CA2CA7 | |
| SCHEMBL2707268 | 0.82 | TDP1 (0.34) | CYP2D6NR1D1CA1CA2CA7 | |
| SCHEMBL9339020 | 0.81 | CA12 (0.33) | CYP2D6NR1D1CA1CA2CA7 | |
| Acetic Acid SCHEMBL6839804 | 0.80 | CYP2D6 (0.33) | CYP2D6NR1D1NR1H3 | |
| SCHEMBL5972122 | 0.80 | CTSK (0.31) | CYP2D6CTSK | |
| SCHEMBL3780442 | 0.79 | TDP1 (0.32) | CYP2D6NR1D1 | |
| SCHEMBL15548847 | 0.79 | NR1D1 (0.36) | CYP2D6NR1D1CA1CA2CA7 | |
| SCHEMBL4338902 | 0.78 | CYP2D6 (0.36) | CYP2D6NR1D1CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356932-A | Methods and compositions for controlling intraocular pressure with transition metal complexes | ALCON LABORATORIES, INC. (US) | 1994-10-18 | — | — | US | disclosed |