Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 2/20 | 0.44 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL1052164 | 0.90 | BBOX1 (0.42) | BBOX1FFAR3TSHRALDH1A1LMNA | |
| Bicarbonate SCHEMBL557719 | 0.87 | BBOX1 (0.52) | BBOX1FFAR3TSHRALDH1A1LMNA | |
| Maleic Acid SCHEMBL8536019 | 0.84 | TSHR (0.53) | BBOX1TSHRALDH1A1LMNAAPEX1 | |
| Fumaric Acid SCHEMBL4953868 | 0.84 | TSHR (0.53) | BBOX1TSHRALDH1A1LMNAAPEX1 | |
| Maleic Acid SCHEMBL2451024 | 0.84 | TSHR (0.53) | BBOX1TSHRALDH1A1LMNAAPEX1 | |
| Fumaric Acid SCHEMBL7128186 | 0.84 | TSHR (0.53) | BBOX1TSHRALDH1A1LMNAAPEX1 | |
| Bicarbonate SCHEMBL557717 | 0.83 | BBOX1 (0.54) | BBOX1FFAR3TSHRCA1HDAC3 | |
| Fumaric Acid SCHEMBL4926338 | 0.82 | TSHR (0.50) | BBOX1TSHRALDH1A1LMNAAPEX1 | |
| Maleic Acid SCHEMBL4929193 | 0.82 | TSHR (0.50) | BBOX1TSHRALDH1A1LMNAAPEX1 | |
| Pivalate SCHEMBL4916740 | 0.82 | TSHR (0.38) | BBOX1FFAR3TSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111039910-A | Photoinitiated method for synthesizing 3-aryl flavone or coumarin compound and application thereof | 云南大学 | 2020-04-21 | — | — | CN | claimed |
| CN-107615556-B | Electrolyte and metal hydride battery | 巴斯夫公司 | 2021-11-02 | — | — | CN | disclosed |
| CN-113501779-A | Method for selectively removing benzyl, allyl and propargyl protecting groups initiated by visible light or near visible light | 云南大学 | 2021-10-15 | — | — | CN | disclosed |
| CN-107868053-B | Preparation method of alkyl sulfate | 深圳新宙邦科技股份有限公司 | 2021-05-14 | — | — | CN | disclosed |
| CN-111039910-A | Photoinitiated method for synthesizing 3-aryl flavone or coumarin compound and application thereof | 云南大学 | 2020-04-21 | — | — | CN | disclosed |
| CN-105829375-B | Allophanate-isocyanurateing catalyst, polyisocyanate composition, method for producing the composition, and two-component coating composition | 东曹株式会社 | 2019-09-20 | — | — | CN | disclosed |
| CN-105829375-A | Allophanate-isocyanurateing catalyst, polyisocyanate composition, method for producing the composition, and two-component coating composition | 东曹株式会社 | 2016-08-03 | — | — | CN | disclosed |
| EP-1669383-B1 | CATALYST COMPOSITION FOR PRODUCTION OF RIGID POLYURETHANE FOAM AND ISOCYANURATE-MODIFIED RIGID POLYURETHANE FOAM AND RAW-MATERIAL COMPOSITION CONTAINING THE SAME | TOSOH CORP (JP) | 2014-11-12 | — | — | EP | disclosed |
| US-8877825-B2 | Catalyst composition for production of polyurethane resin and method for producing polyurethane resin | TOSOH CORPORATION (JP) | 2014-11-04 | — | — | US | disclosed |
| US-8779018-B2 | Catalyst composition for production of rigid polyurethane foam and isocyanurate-modified rigid polyurethane foam and raw-material composition containing the same | TOSOH CORPORATION (JP) | 2014-07-15 | — | — | US | disclosed |
| EP-2033257-A4 | ANIONIC FUEL CELLS, HYBRID FUEL CELLS, AND METHODS OF FABRICATION THEREOF | GEORGIA TECH RES INST (US) | 2009-07-01 | — | — | EP | disclosed |
| EP-2050775-A1 | CATALYST COMPOSITION FOR POLYURETHANE RESIN PRODUCTION AND METHOD FOR PRODUCING POLYURETHANE RESIN | Tosoh Corporation (JP) | 2009-04-22 | — | — | EP | disclosed |
| EP-2033257-A2 | ANIONIC FUEL CELLS, HYBRID FUEL CELLS, AND METHODS OF FABRICATION THEREOF | Georgia Tech Research Corporation (US) | 2009-03-11 | — | — | EP | disclosed |
| WO-2008054858-A2 | ANIONIC FUEL CELLS, HYBRID FUEL CELLS, AND METHODS OF FABRICATION THEREOF | GEORGIA TECH RESEARCH CORPORATION (US) | 2008-05-08 | — | — | WO | disclosed |
| US-20070259236-A1 | Anionic fuel cells, hybrid fuel cells, and methods of fabrication thereof | ENERGY, UNITED STATES DEPARTMENT OF | 2007-11-08 | — | — | US | disclosed |
| US-20070112085-A1 | Catalyst composition for production of rigid polyurethane foam and isocyanurate-modified rigid polysurethane foam and raw-material composition containing the same | TOSOH CORPORATION (JP) | 2007-05-17 | — | — | US | disclosed |
| EP-1669383-A1 | CATALYST COMPOSITION FOR PRODUCTION OF RIGID POLYURETHANE FOAM AND ISOCYANURATE-MODIFIED RIGID POLYURETHANE FOAM AND RAW-MATERIAL COMPOSITION CONTAINING THE SAME | Tosoh Corporation (JP) | 2006-06-14 | — | — | EP | disclosed |
| EP-0930540-B1 | PHOTOSENSITIVE COMPOSITION AND USE THEREOF | SANYO CHEMICAL IND LTD (JP) | 2004-06-16 | — | — | EP | disclosed |
| US-6727034-B1 | HIGH SENSITIVITY AND HIGH RESOLUTION; BLACK MATRIX AND PHOSPHOR SCREEN FOR A COLOR PICTURE TUBE | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2004-04-27 | — | — | US | disclosed |
| EP-0930540-A1 | PHOTOSENSITIVE COMPOSITION AND USE THEREOF | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-21 | — | — | EP | disclosed |