Known targets — ChEMBL curated mechanism
ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2BTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3MPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PPARGSLC6A2SLC6A3SLC6A4SMOTYK2pol
The experimentally established mechanism targets of Maleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.53 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.48 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.38 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL4953868 | 1.00 | TSHR (0.53) | TSHRTP53EGLN1EGLN3HCAR2 | |
| Maleic Acid SCHEMBL8536019 | 1.00 | TSHR (0.53) | TSHRTP53EGLN1EGLN3HCAR2 | |
| Fumaric Acid SCHEMBL7128186 | 1.00 | TSHR (0.53) | TSHRTP53EGLN1EGLN3HCAR2 | |
| Maleic Acid SCHEMBL4929193 | 0.97 | TSHR (0.50) | TSHRTP53EGLN1EGLN3HCAR2 | |
| Fumaric Acid SCHEMBL4926338 | 0.97 | TSHR (0.50) | TSHRTP53EGLN1EGLN3HCAR2 | |
| Maleic Acid SCHEMBL4953224 | 0.88 | TSHR (0.53) | TSHRTP53EGLN1EGLN3HCAR2 | |
| Fumaric Acid SCHEMBL4951497 | 0.88 | TSHR (0.53) | TSHRTP53EGLN1EGLN3HCAR2 | |
| Fumaric Acid SCHEMBL4955051 | 0.88 | TSHR (0.53) | TSHRTP53EGLN1EGLN3HCAR2 | |
| Maleic Acid SCHEMBL4953250 | 0.88 | TSHR (0.53) | TSHRTP53EGLN1EGLN3HCAR2 | |
| Fumaric Acid SCHEMBL2457508 | 0.88 | BBOX1 (0.45) | TSHRTP53EGLN1EGLN3HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115312330-B | Super capacitor electrolyte and super capacitor using same | 江苏国泰超威新材料有限公司 | 2022-12-30 | — | — | CN | claimed |
| CN-115312330-A | Super capacitor electrolyte and super capacitor using same | 江苏国泰超威新材料有限公司 | 2022-11-08 | — | — | CN | claimed |
| EP-2003157-A2 | Tetraalkylammonium carboxylate salts as trimerization catalysts for spray foam applications | Air Products and Chemicals, Inc. (US) | 2008-12-17 | — | — | EP | claimed |
| US-5457599-A | Solute for electrolyte is quaternaryammonium salt of caboxylic acid selected from phthalic acid, tetrahydrophthalic acid, maleic acid, hexahydrophthalic acid or an alkyl or nitro substituent of above acids; high temperature stability | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1995-10-10 | — | — | US | claimed |
| JP-9111659-A | — | — | None | — | — | JP | disclosed |
| JP-3091910-A | — | — | None | — | — | JP | disclosed |
| CN-115312330-B | Super capacitor electrolyte and super capacitor using same | 江苏国泰超威新材料有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-115312330-A | Super capacitor electrolyte and super capacitor using same | 江苏国泰超威新材料有限公司 | 2022-11-08 | — | — | CN | disclosed |
| EP-1650328-B1 | METHOD FOR FORMING OXIDE FILM ON METAL SURFACE USING IONIC LIQUID, ELECTROLYTIC CAPACITOR AND ELECTROLYTE THEREOF | KANEKA CORP (JP) | 2016-10-19 | — | — | EP | disclosed |
| EP-2540875-A1 | Electrolytic capacitor including ionic liquid in electrolyte | KANEKA CORPORATION (JP) | 2013-01-02 | — | — | EP | disclosed |
| US-8014128-B2 | Method for forming oxide film on metal surface using ionic liquid, electrolytic capacitor and electrolyte thereof | KANEKA CORPORATION (JP) | 2011-09-06 | — | — | US | disclosed |
| US-7746623-B2 | Electrolytic capacitor and electrolyte thereof | KANEKA CORPORATION (JP) | 2010-06-29 | — | — | US | disclosed |
| CN-1117323-A | Electrolytic solution and electrochemical element prepared therefrom | SANYO CHEMICAL IND LTD (JP) | 1996-02-21 | — | — | CN | disclosed |
| EP-0684620-A1 | ELECTROLYTIC SOLUTION AND ELECTROCHEMICAL ELEMENT PREPARED THEREFROM | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 1995-11-29 | — | — | EP | disclosed |
| EP-0543311-B1 | Electrolytic solution for electrolytic capacitor | NIPPON CHEMICON (JP) | 1995-06-28 | — | — | EP | disclosed |
| US-5338472-A | Mixture of g-butyrolactone and ethylene glycol with quaternary alkylammonium phthalate, maleate or benzoate as solute, also with colloidal silica | NIPPON CHEMI-CON CORPORATION (JP) | 1994-08-16 | — | — | US | disclosed |
| EP-0543311-A2 | Electrolytic solution for electrolytic capacitor | NIPPON CHEMI-CON CORPORATION (JP) | 1993-05-26 | — | — | EP | disclosed |
| JP-H0391910-A | ELECTROLYTE FOR ELECTROLYTIC CAPACITOR | MITSUBISHI PETROCHEM CO LTD | 1991-04-17 | — | — | JP | disclosed |
| US-4892944-A | Process for producing quaternary salts | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1990-01-09 | — | — | US | disclosed |
| EP-0291074-A2 | Process for producing quaternary salts | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1988-11-17 | — | — | EP | disclosed |