Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAA2 | P54646 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | GPR183 | P32249 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5577349 | 0.90 | CHRM3 (0.52) | PRKAA2OPRM1ALDH1A1OPRL1CHRM3 | |
| SCHEMBL5577372 | 0.85 | GPR183 (0.44) | PRKAA2MCHR1ALDH1A1OPRL1CHRM3 | |
| SCHEMBL5577668 | 0.85 | PDE4A (0.52) | POLBMCHR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5577432 | 0.85 | PRKAA2 (0.47) | PRKAA2MCHR1CXCR3CHRM3 | |
| SCHEMBL5577487 | 0.83 | PRKAA2 (0.47) | PRKAA2MCHR1CXCR3GPR183CYP2D6 | |
| SCHEMBL5577711 | 0.82 | PRKAA2 (0.46) | PRKAA2MCHR1CXCR3GPR183CYP2D6 | |
| SCHEMBL5577441 | 0.82 | MCHR1 (0.45) | PRKAA2MCHR1CXCR3CHRM3 | |
| SCHEMBL5577480 | 0.82 | MT-CO2 (0.54) | PRKAA2OPRM1MCHR1SMN1; SMN2OPRL1 | |
| SCHEMBL6355362 | 0.77 | POLB (0.72) | POLBSMN1; SMN2 | |
| SCHEMBL5577460 | 0.77 | CHRM3 (0.50) | ALDH1A1DRD4SMN1; SMN2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-22 | — | — | US | disclosed |
| EP-1616862-A1 | NITROGENOUS HETEROCYCLIC COMPOUND AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | HLA-DRB1, MIF, HLA-C | PRKAA2 4492/4885POLB 3375/4885OPRM1 584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.