Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5577781 | 0.93 | CHRM3 (0.46) | TAS1R3TAS1R1CHRM3KDM4EMAPT | |
| SCHEMBL5577756 | 0.90 | CHRM3 (0.51) | TAS1R3TAS1R1CHRM3KDM4EMAPT | |
| SCHEMBL5577262 | 0.89 | MMP13 (0.53) | CHRM3KDM4EMAPTALDH1A1POLB | |
| SCHEMBL5577805 | 0.89 | CHRM3 (0.56) | CHRM3KDM4EMAPTALDH1A1POLB | |
| SCHEMBL5577792 | 0.88 | CHRM3 (0.51) | CHRM3KDM4EMAPTALDH1A1POLB | |
| SCHEMBL5577883 | 0.86 | CHRM3 (0.55) | CHRM3KDM4EMAPTMEN1KMT2A | |
| SCHEMBL5577743 | 0.86 | MEN1 (0.54) | CHRM3KDM4EALDH1A1POLBMEN1 | |
| SCHEMBL5577789 | 0.85 | CHRM3 (0.51) | CHRM3KDM4EMAPTALDH1A1POLB | |
| SCHEMBL5577509 | 0.84 | CHRM3 (0.50) | TAS1R3TAS1R1CHRM3KDM4EMAPT | |
| SCHEMBL5577632 | 0.81 | KDM4E (0.52) | TAS1R3TAS1R1CHRM3KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-22 | — | — | US | disclosed |
| EP-1616862-A1 | NITROGENOUS HETEROCYCLIC COMPOUND AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | HLA-DRB1, MIF, HLA-C | TAS1R3 4087/4885TAS1R1 3850/4885CHRM3 2099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.