Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.51 |
| ▸ | ACHE | P22303 | 3/20 | 0.51 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13636459 | 0.80 | SLC6A4 (0.51) | SLC6A4OPRM1ACHESLC22A1CHRM2 | |
| SCHEMBL11637989 | 0.78 | SLC6A2 (0.52) | SLC6A4OPRM1SLC22A1CHRM2SLC6A2 | |
| Bromide SCHEMBL11636924 | 0.77 | SLC6A2 (0.51) | SLC6A4OPRM1SLC22A1CHRM2SLC6A2 | |
| SCHEMBL4240600 | 0.77 | SLC6A4 (0.49) | SLC6A4OPRM1ACHESLC22A1CHRM2 | |
| SCHEMBL5089843 | 0.77 | SLC6A4 (0.74) | SLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL11638103 | 0.76 | SLC6A4 (0.47) | SLC6A4OPRM1ACHESLC22A1CHRM2 | |
| SCHEMBL11632321 | 0.75 | SLC6A4 (0.50) | SLC6A4OPRM1ACHESLC22A1CHRM2 | |
| SCHEMBL5089570 | 0.75 | SLC6A4 (0.73) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL9118391 | 0.74 | SLC6A4 (0.69) | SLC6A4OPRM1SLC6A2SLC6A3 | |
| SCHEMBL11081910 | 0.74 | SLC6A4 (0.43) | SLC6A4OPRM1ACHESLC22A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190008849-A1 | ABUSE-PROOFED DOSAGE FORM | Grünenthal GmbH (DE) | 2019-01-10 | — | — | US | disclosed |
| US-20180243237-A1 | ABUSE-PROOFED DOSAGE FORM | Grünenthal GmbH (DE) | 2018-08-30 | — | — | US | disclosed |
| US-10058548-B2 | Abuse-proofed dosage form | Grünenthal GmbH (DE) | 2018-08-28 | — | — | US | disclosed |
| US-20170209379-A1 | ABUSE-PROOFED DOSAGE FORM | Grünenthal GmbH (DE) | 2017-07-27 | — | — | US | disclosed |
| US-9629807-B2 | Abuse-proofed dosage form | Grünenthal GmbH (DE) | 2017-04-25 | — | — | US | disclosed |
| US-20170027886-A1 | Abuse-proofed dosage forms | GRUENENTHAL GMBH (DE) | 2017-02-02 | — | — | US | disclosed |
| US-20160374963-A1 | ABUSE-PROOFED DOSAGE FORM | Grünenthal GmbH (DE) | 2016-12-29 | — | — | US | disclosed |
| US-20160361308-A1 | ABUSE-PROOFED DOSAGE FORM | GRUENENTHAL GMBH (DE) | 2016-12-15 | — | — | US | disclosed |
| US-20160263037-A1 | ABUSE-PROOFED DOSAGE FORM | Grünenthal GmbH (DE) | 2016-09-15 | — | — | US | disclosed |
| US-20160166517-A1 | ABUSE-PROOFED DOSAGE FORM | Grünenthal GmbH (DE) | 2016-06-16 | — | — | US | disclosed |
| US-20130171075-A1 | ABUSE-PROOFED DOSAGE FORM | GRUNENTHAL GMBH (DE) | 2013-07-04 | — | — | US | disclosed |
| US-8420056-B2 | Abuse-proofed dosage form | GRUNENTHAL GMBH (DE) | 2013-04-16 | — | — | US | disclosed |
| US-8192722-B2 | Abuse-proof dosage form | GRUNENTHAL GMBH (DE) | 2012-06-05 | — | — | US | disclosed |
| US-20120034171-A1 | ABUSE-PROOFED DOSAGE FORM | GRUENENTHAL GMBH (DE) | 2012-02-09 | — | — | US | disclosed |
| US-20080311049-A1 | Thermoforming by extrusion without discoloration; controlled release | GRUNENTHAL GMBH (DE) | 2008-12-18 | — | — | US | disclosed |
| US-20080247959-A1 | FORM OF ADMINISTRATION SECURED AGAINST MISUSE | GRUNENTHAL GMBH (DE) | 2008-10-09 | — | — | US | disclosed |
| US-20070183979-A1 | Abuse-proofed dosage form | ENDO PHARMACEUTICALS, INC. | 2007-08-09 | — | — | US | disclosed |
| US-20070183980-A1 | Thermoforming by extrusion without discoloration; controlled release | ENDO PHARMACEUTICALS, INC. | 2007-08-09 | — | — | US | disclosed |
| US-20070048228-A1 | Heat pressing a mixture of an active ingredient with abuse potential, a high strength polymer, and a wax into a controlled release dosage form | ENDO PHARMACEUTICALS INC. | 2007-03-01 | — | — | US | disclosed |
| US-20060193782-A1 | Abuse-proofed dosage form | ENDO PHARMACEUTICALS, INC. | 2006-08-31 | — | — | US | disclosed |