Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.51 |
| ▸ | ACHE | P22303 | 3/20 | 0.51 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4240600 | 0.81 | SLC6A4 (0.49) | SLC6A4ACHESLC22A1CHRM2OPRM1 | |
| SCHEMBL557756 | 0.80 | SLC6A4 (0.51) | SLC6A4ACHESLC22A1CHRM2OPRM1 | |
| SCHEMBL2864514 | 0.79 | DPP4 (0.68) | SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL10669389 | 0.78 | DPP4 (0.66) | SLC6A4SLC6A3 | |
| SCHEMBL10208913 | 0.77 | DPP4 (0.70) | SLC6A4SLC6A3 | |
| SCHEMBL2499568 | 0.76 | HSD11B1 (0.56) | SLC6A4ACHESLC22A1CHRM2OPRM1 | |
| SCHEMBL11632321 | 0.76 | SLC6A4 (0.50) | SLC6A4ACHESLC22A1CHRM2OPRM1 | |
| SCHEMBL5140924 | 0.74 | SLC6A4 (0.77) | SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL10669384 | 0.74 | KDM1A (0.48) | SLC6A4SLC6A3 | |
| SCHEMBL8866416 | 0.74 | CYP2D6 (0.55) | SLC6A4CYP2D6SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615893-B1 | 2-AZABICYCLO¬3.3.1 NONANE DERIVATIVES AS OPIOID RECEPTOR ANTAGONISTS | PFIZER PROD INC (US) | 2009-11-18 | — | — | EP | disclosed |