Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.49 |
| ▸ | ACHE | P22303 | 3/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13636459 | 0.81 | SLC6A4 (0.51) | SLC6A4ACHEOPRM1SLC22A1CHRM2 | |
| SCHEMBL557756 | 0.77 | SLC6A4 (0.51) | SLC6A4ACHEOPRM1SLC22A1CHRM2 | |
| SCHEMBL11632321 | 0.73 | SLC6A4 (0.50) | SLC6A4ACHEOPRM1SLC22A1CHRM2 | |
| SCHEMBL2499568 | 0.71 | HSD11B1 (0.56) | SLC6A4ACHEOPRM1SLC22A1CHRM2 | |
| SCHEMBL2505252 | 0.69 | SLC6A4 (0.49) | SLC6A4ACHEOPRM1SLC22A1CHRM2 | |
| SCHEMBL5808986 | 0.69 | OPRD1 (0.67) | SLC6A4ACHEOPRM1SLC22A1CHRM2 | |
| SCHEMBL30475863 | 0.68 | ESR1 (0.57) | SLC6A4ACHEOPRM1SLC22A1CHRM2 | |
| SCHEMBL6656340 | 0.67 | ACHE (0.46) | SLC6A4ACHEOPRM1SLC22A1CHRM2 | |
| SCHEMBL542062 | 0.67 | ACHE (0.77) | SLC6A4ACHEOPRM1SLC22A1CHRM2 | |
| SCHEMBL7674020 | 0.67 | SLC6A4 (0.59) | SLC6A4ACHEOPRM1SLC22A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11224576-B2 | Process for the production of an abuse-proofed dosage form | Grünenthal GmbH (DE) | 2022-01-18 | — | — | US | disclosed |
| US-10729658-B2 | Process for the production of an abuse-proofed dosage form | Grünenthal GmbH (DE) | 2020-08-04 | — | — | US | disclosed |
| US-20160367487-A1 | PROCESS FOR THE PRODUCTION OF AN ABUSE-PROOFED DOSAGE FORM | Grünenthal GmbH (DE) | 2016-12-22 | — | — | US | disclosed |
| US-20160367486-A1 | PROCESS FOR THE PRODUCTION OF AN ABUSE-PROOFED DOSAGE FORM | Grünenthal GmbH (DE) | 2016-12-22 | — | — | US | disclosed |
| US-20160367485-A1 | PROCESS FOR THE PRODUCTION OF AN ABUSE-PROOFED DOSAGE FORM | Grünenthal GmbH (DE) | 2016-12-22 | — | — | US | disclosed |
| US-20150283086-A1 | PROCESS FOR THE PRODUCTION OF AN ABUSE-PROOFED DOSAGE FORM | Grünenthal GmbH (DE) | 2015-10-08 | — | — | US | disclosed |
| US-20150164811-A1 | PROCESS FOR THE PRODUCTION OF AN ABUSE-PROOFED DOSAGE FORM | Grünenthal GmbH (DE) | 2015-06-18 | — | — | US | disclosed |
| US-20150091201-A1 | PROCESS FOR THE PRODUCTION OF AN ABUSE-PROOFED DOSAGE FORM | Grünenthal GmbH (DE) | 2015-04-02 | — | — | US | disclosed |
| US-8722086-B2 | Dosage form with impeded abuse | GRUENENTHAL GMBH (DE) | 2014-05-13 | — | — | US | disclosed |
| EP-1740156-B8 | METHOD FOR THE PRODUCTION OF AN ABUSE-PROOF, SOLID FORM OF ADMINISTRATION | GRUENENTHAL GMBH (DE) | 2012-07-11 | — | — | EP | disclosed |
| EP-1699440-A1 | METHOD FOR THE PRODUCTION OF AN ADMINISTRATION FORM WHICH IS SECURED AGAINST MISUSE | Grünenthal GmbH (DE) | 2006-09-13 | — | — | EP | disclosed |
| US-20060188447-A1 | Process for the production of an abuse-proofed dosage form | ENDO PHARMACEUTICALS INC. | 2006-08-24 | — | — | US | disclosed |
| EP-1658054-A1 | DOSAGE FORM THAT IS SAFEGUARDED FROM ABUSE | Grünenthal GmbH (DE) | 2006-05-24 | — | — | EP | disclosed |
| EP-1658055-A1 | FORM OF ADMINISTRATION SECURED AGAINST MISUSE | Grünenthal GmbH (DE) | 2006-05-24 | — | — | EP | disclosed |
| WO-2006002883-A1 | METHOD FOR PRODUCING A SOLID DOSAGE FORM, WHICH IS SAFEGUARDED AGAINST ABUSE, WHILE USING A PLANETARY GEAR EXTRUDER | Grünenthal GmbH (DE) | 2006-01-12 | — | — | WO | disclosed |
| WO-2005102294-A2 | TRANSDERMAL SYSTEM SECURED AGAINST MISUSE | Grünenthal GmbH (DE) | 2005-11-03 | — | — | WO | disclosed |
| WO-2005102286-A1 | METHOD FOR THE PRODUCTION OF AN ABUSE-PROOF, SOLID FORM OF ADMINISTRATION | Grünenthal GmbH (DE) | 2005-11-03 | — | — | WO | disclosed |
| WO-2005063214-A1 | METHOD FOR THE PRODUCTION OF AN ADMINISTRATION FORM WHICH IS SECURED AGAINST MISUSE | Grünenthal GmbH (DE) | 2005-07-14 | — | — | WO | disclosed |
| WO-2005016314-A1 | FORM OF ADMINISTRATION SECURED AGAINST MISUSE | Grünenthal GmbH (DE) | 2005-02-24 | — | — | WO | disclosed |
| WO-2005016313-A1 | DOSAGE FORM THAT IS SAFEGUARDED FROM ABUSE | Grünenthal GmbH (DE) | 2005-02-24 | — | — | WO | disclosed |