Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.49 |
| ▸ | WDR5 | P61964 | 2/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | PRKACA | P17612 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | PRKX | P51817 | 1/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5577493 | 0.92 | SMN1; SMN2 (0.58) | SMN1; SMN2CHRM3WDR5ALDH1A1 | |
| SCHEMBL5577722 | 0.92 | SMN1; SMN2 (0.55) | SMN1; SMN2CHRM3WDR5ALDH1A1 | |
| SCHEMBL5577458 | 0.91 | CHRM3 (0.61) | SMN1; SMN2CHRM3WDR5ALDH1A1 | |
| SCHEMBL5577397 | 0.90 | ALDH1A1 (0.55) | SMN1; SMN2CHRM3WDR5ALDH1A1 | |
| SCHEMBL5577442 | 0.89 | CHRM3 (0.58) | SMN1; SMN2CHRM3WDR5ROCK2 | |
| SCHEMBL5577909 | 0.89 | SMN1; SMN2 (0.52) | SMN1; SMN2CHRM3WDR5ALDH1A1 | |
| SCHEMBL5577524 | 0.88 | NAMPT (0.51) | SMN1; SMN2CHRM3WDR5ROCK2CYP3A4 | |
| SCHEMBL5577883 | 0.85 | CHRM3 (0.55) | SMN1; SMN2CHRM3WDR5MAPT | |
| SCHEMBL5577404 | 0.85 | CHRM3 (0.50) | SMN1; SMN2CHRM3WDR5ROCK2CYP3A4 | |
| SCHEMBL5577666 | 0.84 | CHRM3 (0.52) | SMN1; SMN2CHRM3WDR5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-22 | — | — | US | disclosed |
| EP-1616862-A1 | NITROGENOUS HETEROCYCLIC COMPOUND AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | HLA-DRB1, MIF, HLA-C | SMN1; SMN2 2012/4885CHRM3 2099/4885WDR5 3319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.