Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.81 |
| ▸ | RAB9A | P51151 | 7/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.81 |
| ▸ | HPGD | P15428 | 1/20 | 0.81 |
| ▸ | TSHR | P16473 | 1/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.81 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.81 |
| ▸ | KDR | P35968 | 8/20 | 0.71 |
| ▸ | MITF | O75030 | 1/20 | 0.64 |
| ▸ | XBP1 | P17861 | 1/20 | 0.64 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.64 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.63 |
| ▸ | RELA | Q04206 | 1/20 | 0.63 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL935558 | 0.90 | NPC1 (0.70) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL5578232 | 0.87 | KDR (0.67) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL945450 | 0.87 | NPC1 (0.64) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL14379889 | 0.86 | TERT (0.80) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL6084063 | 0.85 | SMN1; SMN2 (0.71) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL995474 | 0.83 | KDR (1.00) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL27866684 | 0.82 | NPC1 (0.80) | NPC1RAB9AKDM4EALDH1A1TSHR | |
| SCHEMBL5263150 | 0.82 | KDR (0.63) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL651159 | 0.81 | KDR (0.74) | NPC1RAB9AKDM4EALDH1A1TSHR | |
| SCHEMBL14461305 | 0.80 | HDAC1 (0.72) | NPC1RAB9AKDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232572-A1 | Chemical derivatives as antitelomerase agents which bind specifically to the G-quadruplex DNA structures and their application as a specific anticancer agent | AVENTIS PHARMA S.A. (FR) | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232572-A1 | Chemical derivatives as antitelomerase agents which bind specifically to the G-quadruplex DNA structures and their application as a specific anticancer agent | DDX21, DNASE1L3, NTPCR | NPC1 4317/4885RAB9A 3961/4885KDM4E 2663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.