Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.46 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.40 |
| ▸ | NPY4R | P50391 | 9/20 | 0.40 |
| ▸ | NPY1R | P25929 | 5/20 | 0.40 |
| ▸ | NPY2R | P49146 | 4/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.40 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | RRM1 | P23921 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697740 | 1.00 | GNAI3 (0.46) | GNAI3GNAO1GNAI1DPP7DPP8 | |
| SCHEMBL4586183 | 1.00 | GNAI3 (0.46) | GNAI3GNAO1GNAI1DPP7DPP8 | |
| SCHEMBL4586178 | 1.00 | GNAI3 (0.46) | GNAI3GNAO1GNAI1DPP7DPP8 | |
| SCHEMBL2183420 | 0.93 | NPY4R (0.41) | GNAI3GNAO1GNAI1DPP7DPP8 | |
| SCHEMBL1521188 | 0.93 | NPY4R (0.41) | GNAI3GNAO1GNAI1DPP7DPP8 | |
| SCHEMBL1521191 | 0.93 | NPY4R (0.41) | GNAI3GNAO1GNAI1DPP7DPP8 | |
| SCHEMBL15263460 | 0.88 | NPY4R (0.48) | GNAI3GNAO1GNAI1NPY4RNPY1R | |
| SCHEMBL3043193 | 0.88 | NPY4R (0.43) | GNAI3GNAO1GNAI1NPY4RNPY1R | |
| SCHEMBL2185394 | 0.87 | NPY4R (0.58) | GNAI3GNAO1GNAI1NPY4RNPY1R | |
| SCHEMBL2195938 | 0.87 | NPY4R (0.49) | GNAI3GNAO1GNAI1DPP7NPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811401-A | Advanced glycosylation endproducts and methods of use therefor | THE PICOWER INSTITUTE FOR MEDICAL RESEARCH (US) | 1998-09-22 | — | — | US | claimed |
| US-4861755-A | Peptides with vasorelaxant, natriuretic and diuretic effects a process for their preparation, agents containing them, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-29 | — | — | US | claimed |
| US-20150307912-A1 | Site-Specific Incorporation of Phosphoserine Into Proteins in Escherichia Coli | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-10-29 | — | — | US | disclosed |
| US-20070248589-A1 | Spatial for Altering Cell Proliferation | VIVINT LLC | 2007-10-25 | — | — | US | disclosed |
| EP-0314576-B1 | TETRA AND PENTAPEPTIDES WITH THE SEQUENCE LYSYL-ARGINYL-ASPARTYL, AND THEIR USE AS ANTITHROMBOTICS | INSTITUT DES VAISSEAUX ET DU SANG (FR) | 1991-05-02 | — | — | EP | disclosed |
| US-4861755-A | Peptides with vasorelaxant, natriuretic and diuretic effects a process for their preparation, agents containing them, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-29 | — | — | US | disclosed |
| EP-0314576-A1 | Tetra and pentapeptides with the sequence lysyl-arginyl-aspartyl, and their use as antithrombotics | INSTITUT DES VAISSEAUX ET DU SANG (FR) | 1989-05-03 | — | — | EP | disclosed |