Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
| ▸ | PPARD | Q03181 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 14/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 14/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 11/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 11/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 11/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 11/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 11/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 11/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 11/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 11/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | LSS | P48449 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5578935 | 0.87 | PPARG (0.45) | PPARGPPARAPPARDHDAC1HDAC2 | |
| SCHEMBL5579015 | 0.73 | PPARA (0.56) | PPARGPPARAPPARD | |
| SCHEMBL15577827 | 0.71 | KDM4E (0.52) | PPARGPPARAPPARDHDAC1HDAC2 | |
| SCHEMBL6557126 | 0.71 | CES1 (0.44) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL29360139 | 0.70 | LSS (0.62) | PPARGPPARAPPARDHDAC1HDAC2 | |
| SCHEMBL9056407 | 0.70 | LSS (0.61) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL3769134 | 0.70 | KCNA3 (0.68) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL7364711 | 0.69 | HDAC3 (0.65) | PPARGPPARAPPARDHDAC1HDAC2 | |
| SCHEMBL9044391 | 0.69 | MAPT (0.55) | PPARGPPARA | |
| SCHEMBL5381503 | 0.69 | ALDH1A1 (0.65) | HDAC1HDAC2HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | BROOKS DAWN A | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | PPARG, NCOA4, PPARA | PPARG 1/4885PPARA 3/4885PPARD 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.