Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2929447 | 0.85 | HCAR2 (0.38) | POLBTSHRKMT2ACYP1A2CYP2C19 | |
| SCHEMBL26816137 | 0.83 | ELANE (0.36) | ALDH1A1MAPTTSHRCYP1A2CYP2C19 | |
| Iodide SCHEMBL5873855 | 0.82 | ELANE (0.36) | ALDH1A1MAPTTSHRCYP1A2CYP2C19 | |
| Iodide SCHEMBL5873850 | 0.82 | ELANE (0.36) | ALDH1A1MAPTTSHRCYP1A2CYP2C19 | |
| SCHEMBL27737972 | 0.80 | ALDH1A1 (0.38) | ALDH1A1CYP3A4POLBMAPTMMP12 | |
| SCHEMBL27758841 | 0.80 | CYP3A4 (0.38) | ALDH1A1CYP3A4POLBMAPTMMP12 | |
| SCHEMBL27315559 | 0.79 | ALDH1A1 (0.40) | ALDH1A1CYP3A4MAPTMMP12TSHR | |
| SCHEMBL16672485 | 0.79 | ESR1 (0.45) | ALDH1A1CYP3A4POLBMAPTMMP12 | |
| SCHEMBL29092768 | 0.78 | POLB (0.50) | ALDH1A1POLBTSHRKMT2ACYP1A2 | |
| SCHEMBL19451976 | 0.78 | ALDH1A1 (0.48) | ALDH1A1CYP3A4MMP12TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3066081-A2 | PROCESS FOR THE PREPARATION OF N-IODOAMIDES | Technion Research & Development Foundation Ltd. (IL) | 2016-09-14 | — | — | EP | disclosed |
| WO-2015068159-A2 | PROCESS FOR THE PREPARATION OF N-IODOAMIDES | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2015-05-14 | — | — | WO | disclosed |
| EP-1859035-A1 | IMMOBILISED ENZYMES | Agency for Science, Technology and Research (SG) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006096132-A1 | IMMOBILISED ENZYMES | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2006-09-14 | — | — | WO | disclosed |